TIAN Xue-jiao, WANG Yan-gang, LI Dian-gui, et al. Medication Laws of Professer LI Dian-gui in Treating Chronic Atrophic Gastritis Based on Data Mining[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(21): 191-196.
DOI:
TIAN Xue-jiao, WANG Yan-gang, LI Dian-gui, et al. Medication Laws of Professer LI Dian-gui in Treating Chronic Atrophic Gastritis Based on Data Mining[J]. Chinese journal of experimental traditional medical formulae, 2016, 22(21): 191-196. DOI: 10.13422/j.cnki.syfjx.2016210191.
Medication Laws of Professer LI Dian-gui in Treating Chronic Atrophic Gastritis Based on Data Mining
Objective: To investigate the medication laws of Professer LI Dian-gui in the treatment of chronic atrophic gastritis (CAG) based on Traditional Chinese Medicine (TCM) Inheritance System (V2.5). Method: The prescriptions from Professer Li in treating CAG were collected and recorded into TCM inheritance system (V2.5). Medication laws and combination regularities were explored and analyzed with the application of data mining methods such as association rules
and clustering algorithm. Result: The analysis showed that 120 prescriptions were involved in the study
and 40 herbs appeared for more than 15 times
mainly including Scutellariae Radix
Pinelliae Rhizoma
Bupleuri Radix
Bamboo Shavings. Most of them were bitter and pungent in flavor and cold in nature
mainly related to stomach
spleen and liver meridians. 22 key herbal combinations and 10 new prescriptions were discovered. Conclusion: With the help of TCM inheritance system
the main therapeutic principle of ‘Clearing Heat and Expelling Dampness
Resolving Turbidity and Removing Toxin’ was explored in the precriptions from Professer Li Dian-gui in treating CAG
and the comprehensive treatment network was established with the characteristics of eliminating dampness
blood stasis
stagnation
accumulation
heat and carbuncles. Drugs with characteristics of ‘acrid opening and bitter downbearing’ were preferred by Professer Li
and the thoughts of ‘resolving dampness by bland percolation’ and ‘transforming dampness with aroma’ were also highlighted
together with the application of insect
mineral and shell drugs. At last
what should not be forgotten was the principle of "creating exits for devils".
Excavation of New Prescription for Chronic Atrophic Gastritis and Its Verification of Syndrome Type of Deficiency of Stomach Yin
Application of Ferroptosis Regulation in Chronic Atrophic Gastritis Based on Spleen Deficiency and Turbid Toxin
Effect of Coptisine on PI3K/Akt/mTOR Signaling Pathway in Chronic Atrophic Gastritis Rats
Current Status of Outcome Indicators in Randomized Controlled Trials of Traditional Chinese Medicine for Treating Chronic Atrophic Gastritis
Clinical Effect of Jianpi Huoxue Prescription Combined with Acupuncture on Chronic Atrophic Gastritis with Gastric Blood Stasis and Its Impact on Inflammatory Indicators and Gastric Mucosal Function
Related Author
SHAO Changming
WANG Hongyu
XIE Shanshan
LIN Baitong
FAN Zhengyang
WANG Fang
LIN Yuyu
ZENG Binfang
Related Institution
Medical Department of Integrated Traditional Chinese and Western Medicine Hospital of Xinjiang Uygur Autonomous Region
College of Traditional Chinese Medicine, Xinjiang Medical University
Hebei University of Chinese Medicine
Hebei Hospital of Chinese Medicine
Hebei Key Laboratory of Turbidity Toxin Syndrome, Key Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research (Hebei), Hebei Provincial Hospital of Traditional Chinese Medicine