Autoimmune hepatitis (AIH) is a severe progressive disease mediated by abnormal autoimmune reactions. Its etiology and pathogenesis are not yet clear. Epidemiological survey shows that AIH is a recurrent disease and the incidence rate is increasing year by year. Patients can quickly progress to cirrhosis and liver failure

or fulminant or sub-fulminant liver disease. In western medicine

the immunosuppressive agents have been used as the first choice for AIH. Prednisone (and/or prednisolone) monotherapy or combined with azathioprine therapy is recognized as the basic treatment for AIH

and widely used in clinical application. The majority of patients with AIH have a good response to hormones and immunosuppressive agents

but the side effects are obvious in long-term application

and the risk of recurrence is higher after stopping treatment. Therefore

it is still an important research topic to explore new AIH therapy. In clinical practice

the traditional Chinese medicine (TCM) and integrative Chinese and western medicine have achieved a better efficacy in the treatment of AIH

so the treatment conditions for AIH with TCM and integrative Chinese and western medicine would be reviewed and analyzed in this paper

hoping to provide a new perspective for the treatment of AIH.