Objective: To discuss the efficacy of Bailing capsules combined with Bufei Huoxue capsules in treating chronic obstructive pulmonary diseases at stationary phase

and their effect on immunologic function

interleukin-10 (IL-10) and interleukin-17 (IL-17). Method: One hundred and sixteen-eight patients were divided into control group (83 cases) and observation group (85 cases) by random number table. Patients in control group got salmeterol and fluticasone propionate inhalation 25 μg/time

bid

as well as nourishment

oxygen therapy and guidance of health education for disease. In addition to the therapy of control group

patients in observation group was also given Bailing capsules

3 gains/time

tid

and Bufei Huoxue capsules

4 gains/time

tid. A follow-up visit was made once every 2 weeks

and the courses of treatment were 24 weeks. Frequency of acute exacerbation COPD and duration were recorded within 24 weeks. And frequency and duration of cold attacks were recorded within 24 weeks. Symptoms

signs

syndrome of qi deficiency of lung and kidney

improved version of the British Medical Research Council respiratory questionnaire (mMRC)

self-assessment test questionnaire for patients with chronic obstructive pulmonary disease and St George's respiratory questionnaire(SGRQ)were scored. Before and after treatment

lung function was detected. Forced vital capacity (FVC)

forced expiratory volume for 1 second (FEV1) and FEV1% were recorded. Levels of IgG

IgM

IgA

alexin C3 and C4 and IL-17 and IL-10 were detected. Result: Through analysis on Ridit

the total rate of TCM symptoms in observation group was superior to that in control group (P<0.05). Scores of cough

sputum expectoration

puffing

chest distress

short breathe

weakness

cyanosis

syndrome of qi deficiency of lung and kidney

mMRC and CAT in observation group were lower than those in control group (P<0.01). After treatment

FVC

FEV1 and FEV1% in observation group were higher than those in control group (P<0.05). SGRQ scale's three scores scale and total score in observation group were lower than those in control group (P<0.01). Level of IL-17 in observation group was lower than that in control group

and level of IL-10

IgG

IgM and IgA in observation group were higher than that in control group (P<0.01). And there was no statistical significance in the differences of alexin C3 and C4 between the two groups. During the 24-week observation

both of frequency and duration of acute exacerbation COPD and cold in control group were lower than those in control group (P<0.01). Conclusion: Bailing capsules combined with Bufei Huoxue capsules can control symptoms

ameliorate lung function

improve quality of life and immune function of organism

relieve inflammatory reaction

stabilize condition and promote recovery of lung for patients of chronic obstructive pulmonary diseases at stationary phase with syndrome of qi deficiency of lung and kidney.