GC-MS Study on Characteristics of Xiaojin Pills Containing Natural Musk and Artificial Musk

YUAN LYu-yi; CHEN Juan; CHANG Yan; TANG Xiao-yin; Brian McGarvey; WANG Xiao-ling

doi:10.13422/j.cnki.syfjx.2017020043

您当前的位置：

首页 >

文章列表页 >

GC-MS Study on Characteristics of Xiaojin Pills Containing Natural Musk and Artificial Musk

更新时间：2024-01-04

- GC-MS Study on Characteristics of Xiaojin Pills Containing Natural Musk and Artificial Musk
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 23, Issue 2, Pages: 43-47(2017)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2017020043
  CLC： O657.63;R286.0
- Published：2017
- 稿件说明：
移动端阅览
YUAN LYu-yi, CHEN Juan, CHANG Yan, et al. GC-MS Study on Characteristics of Xiaojin Pills Containing Natural Musk and Artificial Musk[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(2): 43-47.
DOI：

YUAN LYu-yi, CHEN Juan, CHANG Yan, et al. GC-MS Study on Characteristics of Xiaojin Pills Containing Natural Musk and Artificial Musk[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(2): 43-47. DOI： 10.13422/j.cnki.syfjx.2017020043.

摘要

目的：建立GC-MS法分析小金丸中的特征成分。方法：采用无水乙醇超声提取小金丸中的挥发性成分，再采用气相色谱-质谱联用技术和自动质谱解卷积定性系统（AMDIS）对其特征成分进行定性分析。结果：共鉴定出53个化学成分，含天然麝香小金丸中鉴定出30个化合物，而含人工麝香小金丸中鉴定出23个化合物。含天然麝香小金丸中检测出7个特征成分，分别是棕榈酸乙酯；乙酸脱氢异雄甾酮；3-乙基-3-羟基-雄甾烷-17-酮；去氢表雄酮；雄甾酮；3，17-二酮雄甾烷；3，17-二醇雄甾烷，其相对质量分数分别为0.11%，1.12%，2.80%，1.59%，0.56%，1.99%，1.22%。特征成分中的甾体类化合物来自于天然麝香，酯类化合物可能是天然麝香中的某些化合物与其他药物配伍反应生成的物质。结论：该方法特征性强、方法简便、重复性好，为区分含天然麝香小金丸和含人工麝香小金丸提供参考依据。

Abstract

Objective: To establish the GC-MS analysis method for the identification of Xiaojin pills. Method: The volatile compounds in Xiaojin pills were extracted by ethanol

whose chemical constituents were then analyzed by gas chromatography-mass spectrum (GC-MS) and AMDIS. Result: A total of 53 compounds were identified

30 compounds were identified from Xiaojin pills containing natural moschus

23 compounds were identified from Xiaojin pills containing artificial musk. There are 7 characteristic compounds from Xiaojin pills containing natural musk

including palmitic acid ethyl ester

dehydroisoandrosterone 3-acetate

3-ethyl-3-hydroxy-androstan-17-one

dehydroepiandrosterone

androsterone

androstan-3

17-dione

androstane-3

17-diol

their relative contents were 0.11%

1.12%

2.80%

1.59%

0.56%

1.99%and 1.22%. The steroidal compounds in the characteristic compounds are derived from natural musk

and the ester compound may be a substance produced by the compatibility of some compounds of natural musk with other drugs. Conclusion: This method is characteristic

simple and reproducible

which provides a reference for the distinction Xiaojin pills containing natural-musk and artificial-musk.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effect of Corn Silk on Adipose Tissues in Type 2 Diabetic Rats Based on GC-MS

Analysis and Significance of Autophagy in Liver Cancer Cells Induced by Traditional Chinese Medicine

Analysis of Volatile Oils from the Leaves of Cheval.by GC-MS

GC-MS Analysis of Essential Oils from

Related Author

Wen-ting DONG

Jian-feng SUN

ZHUANG-Yan

Wei-ming WANG

Ya-gang SONG

Lin-lin CUI

Yan LI

Ming-san MIAO

Related Institution

Institute of Traditional Chinese Medicine， Heilongjiang Academy of Chinese Medical Sciences

Henan University of Chinese Medicine

Department of Pharmacy,Jiangxi University of Traditional Chinese Medicine

School of Pharmacy,Shandong University of Traditional Chinese Medicine

College of Chinese Materia Medica,Tianjin University of Traditional Chinese Medicine

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰