HUANG Chun-yu, ZHOU Guo, LI Gang, et al. Effect of Compound Danshen Dripping Pills Combined with Auricular Point Sticking and Acupoint Massage on Stable Angina Pectoris[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(2): 175-180.
DOI:
HUANG Chun-yu, ZHOU Guo, LI Gang, et al. Effect of Compound Danshen Dripping Pills Combined with Auricular Point Sticking and Acupoint Massage on Stable Angina Pectoris[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(2): 175-180. DOI: 10.13422/j.cnki.syfjx.2017020175.
Effect of Compound Danshen Dripping Pills Combined with Auricular Point Sticking and Acupoint Massage on Stable Angina Pectoris
Objective: To observe the effects of compound Danshen dripping pills combined with auricular point sticking and acupoint massage on the quality of life and ischemia events in patients with stable angina pectoris (blood stasis syndrome). Method: One hundred and eighty patients were randomly divided into control group (90 cases) and observation group (90 cases) by visiting sequence according to random number table. Based on non-drug intervention
patients in control group took Bayaspirin enteric-coated tablets
0.1 g/time
1 time/day. Rosuvastatin calcium tablets
5 mg/time
1 time/day. Nifedipine tablets
10 mg/time
1 time/day; nitroglycerin tablets
sublingual buccal immunotherapy in necessity
0.5 mg/time. Routine westem medicine on based the control group
patients in observation group added compound Danshen dripping pills
10 pills/time
3 times/day
sublingual buccal therapy. Combined with auricular point sticking and acupoint massage. The treatment course was 6 months for both groups
and 6 months of follow-up were recorded. Before and after treatment
scores of Seattle Angina Questionnaire (SAQ) and blood stasis syndrome were graded. Stopping or reducing rate of the Nitroglycerin tablets and episode of angina were recorded. Electrocardiogram examination was taken and ischemia events in 12 months were recorded for safety evaluation. Result: The total clinical effective rate for angina pectoris was 87.78% in observation group
higher than 74.44% in control group (χ2=5.221
P<0.05). The total clinical effective rate for electrocardiogram examination was 88.89% in observation group
higher than 76.67% in control group (χ2=4.715
P<0.05). The total clinical effective rate for traditional Chinese medicine(TCM) syndrome was 90% in observation group
higher than 62.22% in control group (χ2=19.096
P<0.05). After treatment
the onset number of angina pectoris and dosage of nitroglycerin in observation group were lower than those in control group for every month (P<0.01). Scores of physical limitation
anginal stability
episode of angina
satisfaction degree with treatment
disease perception of SAQ and the total score in observation group were all higher than those in control group (P<0.01). Stopping or reducing rate of the Nitroglycerin tablets in observation group was higher than that in control group (χ2=4.357
P<0.05). The incidence of cardiac ischemic events in observation group was 6.67%
lower than 17.78% in control group (χ2=5.178
P<0.05). There was no statistically significant difference in incidence of adverse reactions between two groups. Conclusion: Based on the treatment of western medicine routine treatment
compound Danshen dripping pills combined with auricular point sticking and acupoint massage can reduce occurrence of angina pectoris
decrease the dosage of nitroglycerin
ameliorate symptoms
improve quality of life
reduce incidence of ischemic events
and increase clinical efficacy with good safety in the patients with stable angina pectoris blood stasis syndrome.
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Related Author
ZHU Qin-ying
HUANG Xue-lian
TANG Ling
ZHANG Yibin
LU Qi
WANG Baitong
QI Yixun
XU Hanying
Related Institution
Changchun University of Chinese Medicine
The Third Affiliated Clinical Hospital of Changchun University of Chinese Medicine
The Affiliated Hospital of Changchun University of Chinese Medicine
National Clincial Research Center for Cardiovascular Diseases of Traditional Chinese Medicine, Xiyuan Hospital,China Academy of Chinese Medical Sciences
Shanghai Municipal Hospital of Traditional Chinese Medicine (TCM) Affiliated to Shanghai University of TCM