YANG Fei, FAN Bin, YAO Guang-tao, et al. Traditional Chinese Medicine Clinical Treatment and Pharmacology of Tinea Manuum and Pedis[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(2): 207-212.
DOI:
YANG Fei, FAN Bin, YAO Guang-tao, et al. Traditional Chinese Medicine Clinical Treatment and Pharmacology of Tinea Manuum and Pedis[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(2): 207-212. DOI: 10.13422/j.cnki.syfjx.2017020207.
Traditional Chinese Medicine Clinical Treatment and Pharmacology of Tinea Manuum and Pedis
Tinea manuum and pedis is a type of common fungal infectious disease with recurrence in dermatology department of hospital. Clinically
they can be classified into blister-scale type
keratotic type and impregnated erosive type. The main pathogenic fungi include Trichophyton rubrum and Candida albicans. Although tinea manuum and pedis has a high incidence rate in China
it has not currently attracted enough attention compared with other dermatological diseases
thus been included into fewer researches. Now
three commonly used therapies include western medicine
traditional Chinese medicine (TCM) and integrated western medicine and TCM. Western medicine therapy usually involves anti-fungal medicines for external use or oral administration; however
some of the medicines for external use can cause drug resistance
recurrence after discontinuance and adverse reactions
like hepatotoxicity. Compared with western medicines
TCM
with a long application history
are effective with limited side effects. The literatures about the treatment for tinea manuum and pedis with TCM in the past 10 years are systematically searched and collected. Based on the disease etiology and pathogenesis
the basic principles of ‘removing heat
eliminating dampness
sterilizing and relieve itching’ have been established for treating tinea manuum and pedis
and the formulations are summarized. The efficacy and pharmacological effect of single herb are analyzed through an analysis on formulation components and pharmacological research for modern Chinese medicines. Afterwards
the clinical values of TCM are further elaborated. Through the analysis of previous and recent researches on the treatment of tinea manuum and pedis by TCM
limitations are investigated in aspects of preparation process and quality control standard
pharmacological effect and toxicology
and evaluation of clinical efficacy
in the expectation of providing more ideas and methods for improving TCM therapies for tinea manuum and pedis.