Application of Dynamic Optimization Method in Extraction Process Optimization of Ginseng Radix et Rhizoma

CHEN Shi-tao; ZHA Qin; ZHANG Jun; CHEN Sha; LIU An

doi:10.13422/j.cnki.syfjx.2017040043

您当前的位置：

首页 >

文章列表页 >

Application of Dynamic Optimization Method in Extraction Process Optimization of Ginseng Radix et Rhizoma

更新时间：2024-01-04

- Application of Dynamic Optimization Method in Extraction Process Optimization of Ginseng Radix et Rhizoma
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 23, Issue 4, Pages: 43-46(2017)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2017040043
  CLC： R284.2
- Published：2017
- 稿件说明：
移动端阅览
CHEN Shi-tao, ZHA Qin, ZHANG Jun, et al. Application of Dynamic Optimization Method in Extraction Process Optimization of Ginseng Radix et Rhizoma[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(4): 43-46.
DOI：

CHEN Shi-tao, ZHA Qin, ZHANG Jun, et al. Application of Dynamic Optimization Method in Extraction Process Optimization of Ginseng Radix et Rhizoma[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(4): 43-46. DOI： 10.13422/j.cnki.syfjx.2017040043.

摘要

目的：采用动态优化方法优选人参中人参皂苷提取工艺。方法：采用HPLC测定人参中人参皂苷Rg1，人参皂苷Re和人参皂苷Rb1的含量变化，Diamonsil RP-18e色谱柱（4.6 mm×250 mm，5 μm），流动相乙腈（A）-水（B）梯度洗脱（0~7 min，16%~18% A；7~27 min，18%~30% A），流速3.0 mL·min-1，柱温35℃，DAD检测波长203 nm，进样量20 μL。通过比较动态优化工艺与文献提取工艺所得人参提取物中浸膏得率、指标成分含量和指纹图谱的相似度，评价动态优化方法应用于人参中人参皂苷提取工艺优化的可行性。结果：动态优化提取工艺为8倍量70%乙醇提取3次，提取时间为第1次40 min，第2次20 min，第3次40 min，总提取物的浸膏得率为41.3 mg·g-1。动态优化提取工艺与文献提取工艺的提取物中指标成分含量及浸膏得率的RSD均<5%，指纹图谱相似度为100%，表明2种提取方法的提取物基本一致，但是动态优化提取工艺提取时间节约63%，耗电量节约60%。结论：动态优化方法可以用于人参中人参皂苷提取的工业化生产，该工艺能大幅减少提取时间，缩短生产周期，降低能耗，能够产生明显的经济价值，具有很好的应用前景。

Abstract

Objective: To develope a dynamic optimization technique (DOT) method for the extraction of ginsenosides from ginseng slices. Method: The contents of three major ginsenosides (Rg1

Re and Rb1) were determined by HPLC. The extraction yield

contents of ginsenosides and fingerprints similarity were compared between the DOT method and literature extraction process

to evaluate the feasibility of DOT in optimizing the extraction of ginsenosides from ginseng slices. Result: The dynamic optimization process was extracting for thrice with 8 times by 70% ethanol

and extracting time was 40

and 40 minutes in turn with a total extract yield of 41.3 mg·g-1. The extract between DOT process and the literature extraction process was basically the same

but the DOT extraction method could save 63% of extraction time and 60% of power consumption. Conclusion: DOT extraction method can provide shorter extraction time and lower energy cost in the industrial production of ginsenosides from Ginsen Radix et Rhizoma

and it can produce obvious economic value.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Application of Dynamic Optimization Method for Extraction Time of Arctii Fructus in Vitamin C Yinqiao Pian

Differences in Intestinal Absorption Characteristics of Nanophase in Single and Combined Decoctions of Ginseng Radix et Rhizoma and Zingiberis Rhizoma Recens Based on Everted Gut Sac Model

Exploring Effect of Concentration on Quantitative Accuracy of QAMS by Taking Ginsenosides as an Example

Analysis on Determination and Quantity Transfer of Standard Decoction of Ginseng Radix et Rhizoma by Fresh and Traditional Cutting

Related Author

YANG Shi-lin

WANG Yue-sheng

GUO Xiaomeng

WANG Qi

LI Meijing

ZHANG Nan

GONG Muxin

CHEN Xi

Related Institution

Beijing Key Laboratory of Traditional Chinese Medicine（TCM） Collateral Disease Theory Research，School of TCM，Capital Medical University

Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

The 3rd Affiliated Hospital of Changchun University of Chinese Medicine

School of Pharmaceutical Sciences， Changchun University of Chinese Medicine

Key Research Laboratory of National Administration of Traditional Chinese Medicine（Luobing of Cardio-cerebral Vessel）， Hebei Yiling Medical Research Institute

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰