Quality Evaluation of Standard Decoction of Gardeniae Fructus

XU Jiao; CHAO Jung; DAI Yun-tao; ZHU Chao; LI Qi; YOUTIAN Jian-jiu; FAN Zi-quan; WANG Dan-dan

doi:10.13422/j.cnki.syfjx.2017070030

您当前的位置：

首页 >

文章列表页 >

Quality Evaluation of Standard Decoction of Gardeniae Fructus

更新时间：2024-01-04

- Quality Evaluation of Standard Decoction of Gardeniae Fructus
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 23, Issue 7, Pages: 30-35(2017)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.2017070030
  CLC： R286.0
- Published：2017
- 稿件说明：
移动端阅览
XU Jiao, CHAO Jung, DAI Yun-tao, et al. Quality Evaluation of Standard Decoction of Gardeniae Fructus[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(7): 30-35.
DOI：

XU Jiao, CHAO Jung, DAI Yun-tao, et al. Quality Evaluation of Standard Decoction of Gardeniae Fructus[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(7): 30-35. DOI： 10.13422/j.cnki.syfjx.2017070030.

摘要

目的：建立栀子标准汤剂的质量评价方法，为所有源于栀子水提液的制剂的质量标准制定提供参考。方法：制备15批栀子标准汤剂，测定其出膏率、指标成分转移率和pH；建立栀子标准汤剂的UPLC指纹图谱并对主要色谱峰进行质谱鉴定，离子化模式为正、负离子，离子源温度150℃，脱溶剂气体为高纯度氮气，温度550℃，流速800 L·h-1，毛细管电压1.0 kV，锥孔电压30 V，扫描范围m/z 50~1 200。结果：栀子标准汤剂的平均出膏率28.4%，栀子苷转移率77.7%，pH均为4。所有样品的指纹图谱相似度均>0.99，栀子标准汤剂的主要成分为栀子苷。结论：建立的栀子标准汤剂的质量评价方法稳定可行、重复性好，该评价方法灵敏、准确，为所有源于栀子水煎剂的制剂的质量控制提供参考。

Abstract

Objective: To establish quality control methods for standard decoction of Gardeniae Fructus. Method: Fifteen batches of standard decoction of Gardeniae Fructus were prepared and its dry extract rate

transfer rate of index components and pH were calculated.Fingerprints of standard decoction of Gardeniae Fructus were established by UPLC and the main chromatographic peaks were identified by mass spectrometry. Result: The average dry extract rate of standard decoction of Gardeniae Fructus was 28.4%

the transfer rate of geniposide was 77.7% and the pH was 4.The similarities of fingerprints of the standard decoction were >0.99

main component of standard decoction of Gardeniae Fructus was geniposide. Conclusion: Methods for evaluating the quality of standard decoction of Gardeniae Fructus is stable and accurate for quality control of preparations including Gardeniae Fructus water extract.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Quality Evaluation of Standard Decoction of Codonopsis Radix

Quality Evaluation of Standard Decoction of Carthami Flos

Quality Evaluation of Standard Decoction of Angelicae Sinensis Radix

Analysis on Determination and Quantity Transfer of Standard Decoction of Ginseng Radix et Rhizoma by Fresh and Traditional Cutting

Related Author

YU Xiao-hong

ZHAO Kui-jun

MA Zhi-jie

DONG Qing

MA Yu-qin

TONG Jia-yu

QIN Xue-mei

ZHANG Xuejing

Related Institution

School of Pharmaceutical Sciences， Changchun University of Chinese Medicine

The 3rd Affiliated Hospital of Changchun University of Chinese Medicine

College of Biotechnology, Tianjin University of Science & Technology

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences

Waters Technologies (Shanghai) Co. Ltd.

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰