ZOU Jin, YANG Xue-qin, ZHANG Xiao-yong, et al. Medication Regularity of Traditional Chinese Medicine Classical Prescriptions for Depression Based on Apriori and Clustering Algorithm[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(10): 211-215.
DOI:
ZOU Jin, YANG Xue-qin, ZHANG Xiao-yong, et al. Medication Regularity of Traditional Chinese Medicine Classical Prescriptions for Depression Based on Apriori and Clustering Algorithm[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(10): 211-215. DOI: 10.13422/j.cnki.syfjx.2017100211.
Medication Regularity of Traditional Chinese Medicine Classical Prescriptions for Depression Based on Apriori and Clustering Algorithm
Objective: To analyze medication regularity of traditional Chinese medicine(TCM) classical prescriptions for treating depression based on Traditional Chinese Medicine Inheritance Support System(TCMISS). Method: Articles for classical prescriptions treatment for depressionin CNKI
VIP and Wanfang Datas from January 1986 to December 2016 were searched. The data was entered into TCMISS (V2.5) to set up a database
andassociation rules and unsupervised hierarchical clustering were used to analyze common herbs and core combinations and find new prescriptions. Result: Totally 461 cases and 119 prescriptions were screened out
involving 155 herbs. Through analysis
totally 35 frequently used herbs were found
and the top five were Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle
Jujubae Fructus
Bupleuri Radix
Pinelliae Rhizoma
Pinelliae Radix Alba. Totally 25 core combinations were mined through association rules
and three new prescriptions were mined through the cluster analysis from the database. Conclusion: Through TCMISS(V2.5)
TCM classical prescriptionsin the treatment of depression were analyzed to find that frequently used TCM classical prescriptions for treating depression medication frequency are mostly pungent-sweet-warm herbs and those entering heart
spleen and liver and kidney meridians
especially those entering the heart channel. These frequently used TCMs mostly have an effect in replenishing Qi and tonifying spleen
calming nerves and replenishing vital energy
nourishing heart and relieving the depressed liver.Classical prescriptions for treating depression show an effect by activating Yang
nourishing the heart
disperse stagnated liver energy and replenishing spleen Qi
and can provide areference for clinical treatment of depression.
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Related Author
WU Jia-rui
ZHANG Bing
YANG Bing
CHEN Dan
GUO Wei-xian
WU Jia-rui
GAO Rong-rong
ZHONG Meng-liang
Related Institution
Key Laboratory of Chemistry and Engineering of Forest Products, National Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products/Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, School of Chemistry and Chemical Engineering, Guangxi Minzu University
Guangxi Key Laboratory of Chinese Medicine Quality Standard, Guangxi Institute of Chinese Medicine and Pharmaceutical Science
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Beijing University of Chinese Medicine
Guang'anmen Hospital, China Academy of Chinese Medical Sciences