YE Ying, XU Jing, WANG Rui-hai, et al. Research Progress of Garlic Polysaccharide in Chemical, Process Quality, Pharmacology and Application in Past Decade[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(10): 227-234.
DOI:
YE Ying, XU Jing, WANG Rui-hai, et al. Research Progress of Garlic Polysaccharide in Chemical, Process Quality, Pharmacology and Application in Past Decade[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(10): 227-234. DOI: 10.13422/j.cnki.syfjx.2017100227.
Research Progress of Garlic Polysaccharide in Chemical, Process Quality, Pharmacology and Application in Past Decade
Objective: Garlic is a traditional condiment and traditional Chinese medicine
with a good medicinal value. Traditionally
garlic is mainly used for detumescence
detoxification and sterilization. Modern researches showed that garlic is favored by many scholars because of its good pharmacological activities in preventing and treating tumor
reducing hypertension
hyperglycemia
hyperlipidemia and cholesterol
and anti-aging. Garlic mainly contains alliin
garlic neuraminidase
naphtha
saponins
polysaccharides and trace elements. Among them
garlic polysaccharide is one of important chemical components
and one of pharmacodynamic material bases of garlic. With a relative molecular mass ranging between 9-10 kDa
garlic polysaccharide belongs to a type of small molecule heteropolysaccharide. According to hydrolysis
it mainly contains fructose and glucose. Quality control mainly aims to detect total polysaccharide and decomposed monosaccharide content. Garlic polysaccharide content is more than 70%
and can be extracted through refluxing extraction
ultrasonic extraction and enzymatic method. Garlic has such biological activities as enhancement immunity
antioxidation
antivirus
liver protection
myocardial protection
prevention of myocardial fibrosis
and can be developed into healthcare products and medicines. In addition
it can also be used as raw materials in food production. Therefore
it has an important research value and exploitation prospect. The paper has summarized garlic polysaccharide's composition
method of extraction and purification
content determination
pharmacological activity and application
in order to provide a reference for further research