WANG Hu-fang, MO Li-ying, WANG Xing-li, et al. Research Advances in Application of Transglycosylated Stevioside,Hesperidin and Rutin as New Drug Carrier Materials[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(23): 220-227.
DOI:
WANG Hu-fang, MO Li-ying, WANG Xing-li, et al. Research Advances in Application of Transglycosylated Stevioside,Hesperidin and Rutin as New Drug Carrier Materials[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(23): 220-227. DOI: 10.13422/j.cnki.syfjx.2017230220.
Research Advances in Application of Transglycosylated Stevioside,Hesperidin and Rutin as New Drug Carrier Materials
The development of new drug carriers plays an important role in the research of pharmaceutical preparations
with the rapid development of nanotechnology and in-depth understanding of drug carrier.The glycosylation of food additives as a drug carrier research has received extensive attention.In recent years
glycosylated stevioside
glycosylated hesperidin and glycosylated rutin have become research focus.Stevioside
hesperidin and rutin as food additive are widely used in the food industry
they have good biological activity and health function with poor taste and low solubility.Glycosylation modification can increase diversity of their structure and function
so that they can self-assemble in water to form core-shell nano-structure with different aggregation number.Transglycosylated food additives as new drug carriers can increase the solubility of the drug and enhance the bioavailability with good safety.In this paper
the properties and biological safety
biosynthesis method and transglycosylated food additives as well as their application in new drug carrier materials were reviewed so as to provide new method and new thinking for its application in the field of medicine.