DAI Ye-jia, WANG Yun, ZHANG Xue, et al. Research Progress of Quality Control Methods and Pharmacokinetics of Gardeniae Fructus and Its Related Compounds[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(24): 208-216.
DOI:
DAI Ye-jia, WANG Yun, ZHANG Xue, et al. Research Progress of Quality Control Methods and Pharmacokinetics of Gardeniae Fructus and Its Related Compounds[J]. Chinese journal of experimental traditional medical formulae, 2017, 23(24): 208-216. DOI: 10.13422/j.cnki.syfjx.2017240208.
Research Progress of Quality Control Methods and Pharmacokinetics of Gardeniae Fructus and Its Related Compounds
On the basis of quality control of Gardeniae Fructus and its compound
pharmacokinetics of the representative chemical constituents in Gardeniae Fructus and its related compounds were analyzed
such as iridoid glycosides and diterpene pigments.This study summarizes the effects of the monomer administration
compatibility administration
compound administration on pharmacokinetics of active ingredients in Gardeniae Fructus.The results show that the quality control of Gardeniae Fructus and its compound is mainly aimed at the determination and fingerprint of single or multiple index components
but there is still a lack of research on quality control.Pharmacokinetic studies are concerned with the single components in Gardeniae Fructus
which can not reflect the pharmacokinetic characteristics of Gardeniae Fructus.Therefore
in order to provide a useful reference for the clinical use of Gardeniae Fructus
the author thinks that it is necessary to combine the quality control with Chinese medicine chemistry-pharmacological effects-pharmacokinetics and study its pharmacokinetics with multicomponent integration method.