Objective:To analyze and compare the volatile components in different parts of Matricaria chamomilla. Method:The optimum extraction conditions were selected by single factor experiment (the solid phase microextraction fiber head

the sample amount

the extraction temperature

the extraction time and the desorption time) with headspace solid phase microextraction (HS-SPME) method. The chemical compositions in the volatile components extracted with this method from different parts of chamomile were determined by gas chromatography-mass spectrometry (GC-MS)

and their relative mass fraction of each component was determined by area normalization method. Result:The optimum extraction conditions were investigated with 7 major volatile components as indicators. The solid phase microextraction fiber head was PDMS/DVB type; the sample amount was 0.5 g; the extraction temperature was 80℃; the extraction time was 10 min; and the desorption time was 1 min. Furthermore

66 volatile components in M. chamomilla were identified

and 40

31

27

29 and 35 volatile components respectively from the whole herb

flowers

roots

stems and leaves of M. chamomilla

accounting for 84.58%

90.27%

82.41%

87.36% and 82.10% of the total peak areas. Conclusion:The content of volatile components (calculated by the total peak areas) in different parts of M. chamomilla ranged from high to low:leaves > whole herb > flowers > stems > roots. There were 14 common components in all these parts and 25 common components between flowers and whole herb

accounting for 98% and 88% of the identified components in flowers and whole herb respectively. Therefore

the experimental results provide the chemical basis for using the whole herb of M. chamomilla as Uygur medicine.