GUO Hong-wei. Effect of Traditional Chinese Medicine in Antagonizing Post-traumatic Stress Disorder[J]. Chinese journal of experimental traditional medical formulae, 2018, 24(2): 213-219.
DOI:
GUO Hong-wei. Effect of Traditional Chinese Medicine in Antagonizing Post-traumatic Stress Disorder[J]. Chinese journal of experimental traditional medical formulae, 2018, 24(2): 213-219. DOI: 10.13422/j.cnki.syfjx.2018020213.
Effect of Traditional Chinese Medicine in Antagonizing Post-traumatic Stress Disorder
the prevalence of post-traumatic stress disorder (PTSD) has sharply increased because of the increasing major traumatic accidents
such as wars
natural disasters
traffic accidents and violent crimes. PTSD is a long-term persistent mental disorder that is caused by unusual threatening or catastrophic psychological trauma. Over the past decade
the incidence of PTSD has increased year by year
which causes high concerns from the public. This paper retrieved clinical and experimental literatures on treating antagonism of PTSD with traditional Chinese medicine(TCM) collected by CNKI from 2006 to 2016.It also overviewed the effect of TCM in antagonizing PTSD in the following six aspects:scope of TCM syndromes related to PTSD; understanding of etiology and pathogenesis of PTSD in TCM; clinical syndrome differentiation
prescription and medication for PTSD; clinical study on treating PTSD with TCM; clinical study on treating PTSD with acupuncture; experimental study of TCM in antagonizing PTSD. According to the summary and analysis of the retrieved literatures
most scholars classified PTSD into the following categories:Baihe disease
lethargy
palpitations
insomnia
forgetfulness
syncope syndrome
depression syndrome
up-rushing gas syndrome
globus hysteriocus. The clinical syndrome differentiation of PTSD involves heart
liver
spleen
lung and kidney
especially heart and liver. Electro-acupuncture at acupoints has a significant efficacy in the treatment of PTSD. The experimental results of antagonizing PTSD show that the changes in glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) in hippocampus region receptor expression and the regulation of HPA axis are the targets or key links of TCM in antagonizing PTSD. The preliminary analysis was made on the problems in studies on the effect of TCM in antagonizing PTSD.
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Related Institution
The First Affiliated Hospital of Henan University of Chinese Medicine
The First Clinical Medical College, Henan University of Chinese Medicine
Gansu Engineering Laboratory for New Products of Traditional Chinese Medicine (TCM), Gansu Key Laboratory of TCM Excavation and Innovative Transformation,Gansu University of Chinese Medicine
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