Objective:To study the clinical efficacy of Bushen Tiaochong decoction in the obesity patients with polycystic ovarian syndrome (PCOS) and investigate its effect on endometrial receptivity. Method:The 147 obesity patients with PCOS treated in our hospital from June 2014 to July 2016 were selected in the study and divided into two groups according to the random number table

with 73 cases in treatment group and 74 cases in control group. Patients in control group were treated with ethinylestradiol cyproterone combined with letrozole; on this basis

patients in treatment group received additional Bushen Tiaochong decoction. Both groups were treated for 3 menstrual cycles

then the treatment efficacy

reproductive endocrine hormone levels

body mass index (BMI)

fat cell factors and endometrial receptivity were compared. Result:The total effective rate was 90.41% in treatment group

higher than 79.73% in control group (P<0.05). After treatment

the levels of luteotropic hormone (LH)

follicle-stimulating hormone (FSH)

and LH/FSH were significantly decreased while Estradiol (E2) was increased in both groups

and the effect in treatment group was more obvious (P<0.05). After treatment

te levels of visfatin (VF)

leptin (LEP) and BMI were significantly decreased while adiponectin (APN) was increased in both groups

and the effect was more obvious in treatment group (P<0.05). As compared with conditions before treatment

pulsatility index (PI) and resistance index (RI) were decreased in both groups after treatment

while endometrial thickness was increased

and the effect was more obvious in treatment gorup (P<0.05). Conclusion:As a safe and potential method for PCOS

Bushen Tiaochong decoction has better effect on obesity PCOS and can significantly improve reproductive endocrine hormone levels

reduce body mass

and improve endometrial receptivit.