LU Hong-mei, DENG Shao-dong, LU Yang-jia, et al. Research Progress on Oligosaccharides of Morindae Officinalis Radix[J]. Chinese journal of experimental traditional medical formulae, 2018, 24(9): 220-227.
DOI:
LU Hong-mei, DENG Shao-dong, LU Yang-jia, et al. Research Progress on Oligosaccharides of Morindae Officinalis Radix[J]. Chinese journal of experimental traditional medical formulae, 2018, 24(9): 220-227. DOI: 10.13422/j.cnki.syfjx.20180812.
Research Progress on Oligosaccharides of Morindae Officinalis Radix
Morindae Officinalis Radix has a long history of medicinal use in China. It has a wide range of medicinal value and is one of the most commonly used traditional Chinese medicines in clinical application. According to modern studies
oligosaccharides are the main effective components in Morindae Officinalis Radix
with many functions such as anti-dementia
anti-depression
anti-oxidative stress
improving learning and memory ability
and enhancing immunity and sexual function. The above pharmacological actions are of great value for development and utilization. By consulting massive literature materials
it was found that many clinical effects of Morindae Officinalis Radix were correlated with the pharmacological actions of the oligosaccharides. These pharmacological actions have also scientifically interpreted the traditional functions of Morindae Officinalis Radix such as ‘tonifying kidney
dominating bone and benefiting brain’. Therefore
scholars both at home and abroad have done a lot of research work on it
especially the studies on the protective effects of the oligosaccharides from Morindae Officinalis Radix on nervous system. Relevant results showed that it had significant effects in anti-dementia
anti-depression
improving the learning and memory ability
with the potential to develop drugs for the treatment of neurodegenerative disease. In this paper
the researches of the past 20 years on extraction and purification process
component detection method and pharmacological actions of oligosaccharides from Morindae Officinalis Radix were collected and summarized upon accessing multiple databases such as CNKI
WanFang
PubMed
Science Direct and Springer. The researches and development prospects were also analyzed
and the research progress on oligosaccharides from Morindae Officinalis Radix was reviewed for further studying and comprehensive utilization of these oligosaccharides.