MING Hui-yi, MA Xiu-ping, YANG Jing, et al. Research Status of [J]. Chinese journal of experimental traditional medical formulae, 2018, 24(11): 228-234.
DOI:
MING Hui-yi, MA Xiu-ping, YANG Jing, et al. Research Status of [J]. Chinese journal of experimental traditional medical formulae, 2018, 24(11): 228-234. DOI: 10.13422/j.cnki.syfjx.20181019.
Objective: To collect and analyze the reported literature of Melastoma dodecandrum
summarize the paper distribution
chemical compositions
pharmacological activity
quality control
clinical application and patent application status
and provide reference and literature for its clinical application and further development. Method: With “CNKI” and “Pubmed” as the search platform
“key words” and “abstract” as search terms
“diren”
“gagoulu”
“Melastoma dodecandrum Lour.” and “M. dodecandrum” as search words
the papers and patents of M. dodecandrum at home and abroad from 1973 to 2017 were retrieved in this study. Result: 119 papers and 139 patents were obtained
mainly about agriculture and forestry cultivation
chemical composition
quality control and pharmacological activity research in papers
and mainly about compound products in patents. At present
83 chemical constituents were isolated and identified from M. dodecandrum
mainly including flavonoids. Quality control indicators mainly included gallic acid
quercetin and so on
and the pharmacological research was mainly on hypoglycemic effect. Conclusion: M. dodecandrum had significant hemostatic effects with rich resource and high market competitiveness. However
the local standards were not complete
lacking specific indicators to evaluate the quality of medicinal herbs. Therefore
it is necessary to explore the mechanism of hemostasis in depth
study the basis of its active substances
and establish the relationship between spectrum efficiency and efficacy so as to control the quality of medicinal herbs
and promote the utilization and development of natural medicine resources.