Objective: To observe the curative effect of modified Chaihu Shugan San combined with western medicine on benign prostatic hyperplasia (BPH). Method: A total of 88 patients with BPH were divided into two groups. The treatment group (44 cases) was given traditional Chinese medicine(TCM) Chaihu Shugan San combined with western medicine tamsulosin hydrochloride sustained release capsules

and the control group (44 cases) was given western medicine tamsulosin hydrochloride sustained release capsules and Pulean. After 3 months of treatment

the total efficiency

prostate volume (PV)

maximum flow rate(MFR)

bladder residual urine volume (PRV)

serum prostate specific antigen (PSA)

international prostate symptom score (IPSS) and Quality of Life(QOL)

syndrome scores of TCM in two groups were compared. Result: The total effective rates were respectively 87.8% and 76.2% in treatment group and control group

with significant differences (P<0.05). After treatment

the levels of PV

PRV

PSA

IPSS

syndrome scores of TCM were decreased

while MRF

QOL score were increased; some indexes in treatment group were superior to those in control group after treatment(P<0.05

P<0.01). Conclusion: Modified Chaihu Shugan San combined with western medicine has a significant curative effect

and can effectively alleviate the clinical symptoms of patients.