SONG Hong-li, YIN Yu-kun, WANG Yao-han, et al. Effect and Safety of Yishen Gukang Decoction Combined with Oxycontin in Treating Cancer Somatic Pain[J]. Chinese journal of experimental traditional medical formulae, 2018, 24(22): 164-168.
DOI:
SONG Hong-li, YIN Yu-kun, WANG Yao-han, et al. Effect and Safety of Yishen Gukang Decoction Combined with Oxycontin in Treating Cancer Somatic Pain[J]. Chinese journal of experimental traditional medical formulae, 2018, 24(22): 164-168. DOI: 10.13422/j.cnki.syfjx.20182031.
Effect and Safety of Yishen Gukang Decoction Combined with Oxycontin in Treating Cancer Somatic Pain
Objective:To observe the efficacy and safety of Yishen Gukang decoction combined with oxycontin in treating cancer patients with somatic pain. Method:A total of 100 patients with cancer somatic pain treated in Wangjing Hospital from January 2015 to May 2017 were randomly divided into treatment group and control group
with 50 cases in each group. In the first week
both groups were given oxycontin. In the second week
treatment group was additionally given Yishen Gukang decoction
while control group was given placebo. The therapeutic course lasted for 7 days. karnofsky(KPS) score
Karnofsky score
oxycontin dosage and the adverse reactions of the two groups were observed before and after treatment. Result:The total effective rate of treatment group was 94%
with an efficiency rate of 70%; and the total effective rate of control group was 88%
with an efficiency rate of 40%. The curative effect of treatment group was significantly better than that of control group (P<0.01). Moreover
treatment group was better than control group in relieving moderate pain (P<0.01). In Karnofsky score
oxycontin dosage and adverse reactions
treatment group was better than control group (P<0.05). Conclusion:Yishen Gukang decoction can effectively reduce the scores of cancer somatic pain and the oxycontin dosage
and improved the quality of patients' life. It is worth of further clinical promotion and study.
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