Content Determination of 7 Volatile Components in Nvjin Pill by GC

LIN Lin; YU Feng-rui; XU Li-hua; LIN Yong-qiang

doi:10.13422/j.cnki.syfjx.20182413

您当前的位置：

首页 >

文章列表页 >

Content Determination of 7 Volatile Components in Nvjin Pill by GC

更新时间：2024-09-23

- Content Determination of 7 Volatile Components in Nvjin Pill by GC
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 24, Issue 24, Pages: 73-77(2018)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20182413
  CLC： R286.0
- Published：2018
- 稿件说明：
移动端阅览
LIN Lin, YU Feng-rui, XU Li-hua, et al. Content Determination of 7 Volatile Components in Nvjin Pill by GC[J]. Chinese journal of experimental traditional medical formulae, 2018, 24(24): 73-77.
DOI：

LIN Lin, YU Feng-rui, XU Li-hua, et al. Content Determination of 7 Volatile Components in Nvjin Pill by GC[J]. Chinese journal of experimental traditional medical formulae, 2018, 24(24): 73-77. DOI： 10.13422/j.cnki.syfjx.20182413.

摘要

目的：建立同时测定女金丸中桂皮醛、乙酸龙脑酯、丹皮酚、肉豆蔻醚、呋喃莪术二烯酮、藁本内酯和α-香附酮含量的方法。方法：采用HP-5毛细管柱（250 μm×30 m，0.25μm），升温程序为初始温度50℃，保持1 min，以20℃·min-1的速率升温至130℃，保持10 min；再以2℃·min-1的升温速率升至180℃，保持1 min；进样口温度230℃，检测器温度250℃；分流进样，分流比10∶ 1。结果： 7种成分实现完全分离，并与其他成分均能达到良好的分离；桂皮醛、乙酸龙脑酯、丹皮酚、肉豆蔻醚、呋喃莪术二烯酮、藁本内酯和α-香附酮分别在进样量0.013 4～1.342 3，0.003 4～0.343 0，0.023 0～2.302 7，0.017 3～1.728 5，0.030 1～3.008 5，0.017 2～1.724 8，0.003 1～0.308 8 μg与色谱峰峰面积呈良好线性响应；平均回收率（n=6）分别为99.6%，99.4%，99.3%，99.1%，99.8%，99.3%，99.0%；RSD分别为0.4%，0.4%，0.3%，0.2%，0.1%，0.4%，0.5%。结论：该方法多种成分同时测定，操作简便，准确、重复性好，可用于女金丸的质量控制。

Abstract

Objective: To develop a method for simultaneous content determination of cinnamaldehyde

bornyl acetate

paeonol

myristicin

furanodienone

ligustilide and α-cyperone in Nvjin pill. Method: The quantitative analysis was carried out on a capillary column of HP-5(250 μm×30 m

0.25 μm)

temperature programming:initial temperature 50℃

keeping 1 minute

heating up to 130℃ with a rate of 20℃·min-1

keeping 10 minutes

and then heating up to 180℃ with a rate of 2℃·min-1

keeping 1 minute

inlet port temperature 230℃

detector temperature 250℃

split sampling at a split ratio 10:1. Result: The 7 components were completely separated and can be well separated from other components. Cinnamaldehyde

bornyl acetate

paeonol

myristicin

furanodienone

ligustilide and α-cyperone showed a good linear relationship with the chromatographic peak area within the range of 0.013 4-1.342 3

0.003 4-0.343 0

0.023 0-2.302 7

0.017 3-1.728 5

0.030 1-3.008 5

0.017 2-1.724 8

0.003 1-0.308 8 μg respectively. The average recoveries (n=6) were 99.6%

99.4%

99.3%

99.1%

99.8%

99.3% and 99.0%

respectively

with relative standard deviations (RSD) of 0.4%

0.4%

0.3%

0.2%

0.1%

0.4%

0.5%

respectively (n=6). Conclusion: This method is simple

accurate

reproducible and convenient for the quality control over Nvjin pill.

关键词

Keywords

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Color Space Method Combined with Chemometrics to Determine Processing Degree of Angelicae Sinensis Radix Carbonisata

Chemical Constituents， Pharmacological Activities， and Identification of Amomi Fructus： A Review

Structure-activity Omics on Anti-inflammatory and Analgesic Effect of Cyperi Rhizoma in Qizhi Weitong Granules

Angelicae Sinensis Radix in Neurodegenerative Diseases： A Review

Inhibitory Effect of Sesquiterpenoid M36 from Myrrha on Growth of Human Hepatoma Cells

Related Author

QIN Liuying

HUANG Yao

GAN Lifan

LIU Yuanjun

DENG Congyou

SUN Dongmei

LIANG Lijin

ZHOU Lin

Related Institution

Guangdong Provincial Key Laboratory of Traditional Chinese Medicine Formula Granules in Enterprises，Guangdong Efong Pharmaceutical Co. Ltd.

School of Materials Science and Engineering，Guangdong Ocean University

School of Food Science and Engineering，Guangdong Ocean University

China Resources Sanjiu Medical & Pharmaceutical Co. Ltd.

Liaoning Province Modern TCM Research and Engineering Laboratory

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰