Overview of Research on Chinese Medicine Patents for Prevention and Treatment of Asthenopia and Analysis Their Medication Rule

Hao-yue XUE; Yan-bin SHI; Jia-hua JIN; Hong-yu LI

doi:10.13422/j.cnki.syfjx.20190106

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Overview of Research on Chinese Medicine Patents for Prevention and Treatment of Asthenopia and Analysis Their Medication Rule

Data Mining | 更新时间：2021-02-09

- Overview of Research on Chinese Medicine Patents for Prevention and Treatment of Asthenopia and Analysis Their Medication Rule
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 25, Issue 7, Pages: 195-200(2019)
- 作者机构：
  
  1.兰州大学　药学院，兰州　 730000；
  2.上海中华药业南通有限公司，江苏　南通　 226000
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20190106
  CLC： R22;R24;R28;C37;C18;G353.11
- Received：19 June 2018，
  
  Published：05 April 2019
- 稿件说明：
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Hao-yue XUE, Yan-bin SHI, Jia-hua JIN, et al. Overview of Research on Chinese Medicine Patents for Prevention and Treatment of Asthenopia and Analysis Their Medication Rule[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(7): 195-200.
DOI：

Hao-yue XUE, Yan-bin SHI, Jia-hua JIN, et al. Overview of Research on Chinese Medicine Patents for Prevention and Treatment of Asthenopia and Analysis Their Medication Rule[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(7): 195-200. DOI： 10.13422/j.cnki.syfjx.20190106.

摘要

目的：

通过分析中药防治视疲劳领域近20年的专利状况，探讨中药在视疲劳防治过程中的用药规律。

方法：

在IncoPat科技创新情报平台中，对中药防治视疲劳的全球专利进行系统检索，分析专利的申请趋势、类别和法律状态等指标，采用IBM SPSS Modeler 18.0进行关联度分析，比较口服方与外用方的配伍规律与用药差异。

结果：

全球专利申请量逐渐增大，中国占全球中药视疲劳专利申请量的99%以上，在专利申请中常用的类别为药物组合物、口服制剂、外用眼贴和眼罩等，但授权专利占总量比例偏低。在用药规律方面，口服方偏重于滋补肝肾类中药，外用方则偏重于清热明目、芳香开窍类中药。

结论：

国内中药防治视疲劳领域的专利申请数量庞大，但授权率偏低；基于中医理论的中药配伍有规可循，可为防治视疲劳中药产品的研发与推广提供参考。

Abstract

Objective:

To explore drug utilizing regularity of traditional Chinese medicine(TCM) in treating and preventing asthenopia by analyzing the patent status of TCM in the field of asthenopia control for nearly 20 years.

Method:

Global patents about TCM in treating and preventing asthenopia were systematic searched in IncoPat platform.The application trend

legal status and categories of patents were analyzed.Meanwhile

the oral prescriptions and external prescriptions were performed correlation index analysis by IBM SPSS Modeler 18.0

respectively; the difference of compatibility rules between them was compared.

Result:

The number of global patents in treating and preventing asthenopia gradually increased

and the proportion of patents from China was more than 99%.The main patent applications were pharmaceutical composition

oral preparation

external eye patch and so on

but the ratio of licensed patents in total patents was low.In term of drug utilizing regularity

the oral prescriptions paid much attention to using TCM for nourishing the liver and kidney

while external prescriptions highlighted relieving sickness heat and detoxification.

Conclusion:

Patents of TCM in treating and preventing asthenopia has been kept increasing in recent years

but the authorization rate is low.Formulation based on TCM theory can be statistically summarized

which can be helpful for the development of anti-asthenopia products.

关键词

Keywords

references

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