Theoretical and Clinical Studies of Integrated Traditional Chinese Medicine and Western Medicine for Infertile Women with Diminished Ovarian Reserve

Ai-jun SUN; Xu-dong TANG; Qiao-li ZHANG; Jian-ping ZHU; Tian XIA; Can-quan ZHOU; Zhe JIN; Zhao-ling YOU

doi:10.13422/j.cnki.syfjx.20190452

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Theoretical and Clinical Studies of Integrated Traditional Chinese Medicine and Western Medicine for Infertile Women with Diminished Ovarian Reserve

Academic Discussion | 更新时间：2021-02-09

- Theoretical and Clinical Studies of Integrated Traditional Chinese Medicine and Western Medicine for Infertile Women with Diminished Ovarian Reserve
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 25, Issue 8, Pages: 148-157(2019)
- 作者机构：
  
  1.中国医学科学院&北京协和医学院　北京协和医院，北京　 100032;
  2.中国中医科学院　西苑医院，北京　 100091;
  3.首都医科大学　附属北京妇产医院，北京　 100026;
  4.中国中医科学院　中国医史文献研究所，北京　 100700；
  5.天津中医药大学　第一附属医院，天津　 300193;
  6.中山大学　附属第一医院，广州　 510080；
  7.北京中医药大学　东方医院，北京　 100078;
  8.湖南中医药大学　第一附属医院，长沙　 410007
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20190452
  CLC： R2-031;R271.14;R4;C37;R289
- Received：28 October 2018，
  
  Published Online：05 November 2018，
  
  Published：20 April 2019
- 稿件说明：
移动端阅览
Ai-jun SUN, Xu-dong TANG, Qiao-li ZHANG, et al. Theoretical and Clinical Studies of Integrated Traditional Chinese Medicine and Western Medicine for Infertile Women with Diminished Ovarian Reserve[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(8): 148-157.
DOI：

Ai-jun SUN, Xu-dong TANG, Qiao-li ZHANG, et al. Theoretical and Clinical Studies of Integrated Traditional Chinese Medicine and Western Medicine for Infertile Women with Diminished Ovarian Reserve[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(8): 148-157. DOI： 10.13422/j.cnki.syfjx.20190452.

摘要

卵巢储备功能降低(DOR)导致的不孕症业已成为生殖健康领域的难题，引起了国内外学者的广泛关注，其根本病机为肾精亏虚。中医药治疗不孕症历史悠久、经验丰富，针对DOR不孕症，从肾论治。将中西医治疗思想相结合，辨病论治与辨证论治结合，采纳中医专病通治方的理念，确定补肾养血、疏肝健脾的治法治则，组方遣药，通过中药补肾方加减可多系统、多靶点、多环节调节生殖功能，充分发挥中医药优势。同时，提出“长(卵)排(卵)并调，数量质量并举”假说，临床上采用中西医结合的两阶段疗法，达到增加卵泡数量，改善卵泡质量，促进卵泡发育和排出的效果，有效规范治疗DOR不孕症。

Abstract

Infertility with diminished ovarian reserve(DOR) is a major problem in the field of reproductive health and it has attracted great attention worldwidely.Function deficiency of the kidney is one of the fundamental pathogenesis for DOR.Traditional Chinese medicines(TCMs) have a long history with rich experience for the treatment of infertility.Some TCMs are very effective in the treatment of kidney deficiency for infertility with DOR.The integrated TCMs and western medicine

and combination of disease differentiation and syndrome differentiation may help for diagnosis and treatment of infertility with DOR.We adopt the concept of unified treatment for special disease

and the methods and principle of treatment can be used.Therefore

we adopt the TCM concept of kidney-tonifying

blood-nourishing

liver-dispersing and spleen-invigorating.The TCMs kidney-tonifying formulae are added and subtracted.TCMs can regulate the reproductive function via multiple systems for simultaneous conditioning of follicular development and ovulation.At the same time

a hypothesis of " simultaneous conditioning of follicular development and ovulation" was proposed.Two-stage therapy with integrated TCMs and western medicine has been used

mainly for increasing the number of eggs

and improving follicle quality.The goal is to achieve simultaneous conditioning of follicular development and ovulation and ultimately for effective treatment of infertility with DOR.

关键词

Keywords

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