Herbal Textual Research on Genuine Medicinal Materials " Deng Ju" and Quality Evaluation of Nan Yang Chrysanthemi Flos

Peng-fei HAO; Si-yuan ZHANG; Zhi-hui DU; Hua BIAN; Xian-zhang HUANG

doi:10.13422/j.cnki.syfjx.20191211

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Herbal Textual Research on Genuine Medicinal Materials " Deng Ju" and Quality Evaluation of Nan Yang Chrysanthemi Flos

Resource and Quality Evaluation | 更新时间：2021-02-09

- Herbal Textual Research on Genuine Medicinal Materials " Deng Ju" and Quality Evaluation of Nan Yang Chrysanthemi Flos
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 25, Issue 12, Pages: 187-194(2019)
- 作者机构：
  
  1.南阳理工学院　张仲景国医国药学院，河南　南阳　 473000；
  2.南阳理工学院　河南省张仲景方药与免疫调节重点实验室，河南　南阳　 473000
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20191211
  CLC： R284.1; R2-031; R22; R289
- Received：12 July 2018，
  
  Published Online：04 March 2019，
  
  Published：20 June 2019
- 稿件说明：
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Peng-fei HAO, Si-yuan ZHANG, Zhi-hui DU, et al. Herbal Textual Research on Genuine Medicinal Materials " Deng Ju" and Quality Evaluation of Nan Yang Chrysanthemi Flos[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(12): 187-194.
DOI：

Peng-fei HAO, Si-yuan ZHANG, Zhi-hui DU, et al. Herbal Textual Research on Genuine Medicinal Materials " Deng Ju" and Quality Evaluation of Nan Yang Chrysanthemi Flos[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(12): 187-194. DOI： 10.13422/j.cnki.syfjx.20191211.

摘要

目的：

考证南阳菊花的本草源流，溯源其盛衰史，再通过现代分析方法对现今南阳菊花进行品质评价，阐明南阳地产菊花之优势。

方法：

通过考证《中华医典》及相关古文献对南阳菊花的记载，阐明南阳古代菊花的源流、应用，自古文献中揭示南阳菊花与其他菊花品种的亲缘关系；再通过高效液相色谱一测多评法，对14批菊花中的包含2015年版《中国药典》指标在内的8种化学成分进行含量测定，依据结果进行综合加权评分分析；另建立14批菊花的高效液相色谱指纹图谱，并对其进行相似度、聚类分析，以期综合评价现今南阳菊花质量，并从化学成分层面阐明南阳菊花与其他产地菊花的亲缘关系。

结果：

本草考证显示南阳菊花自汉朝以后流传各地，后世众多药用菊花均受南阳菊花之影响；指纹图谱的相似度、聚类分析也进一步证实南阳菊花与多种菊花在化学层面上存在亲缘关系；2015年版《中国药典》指标检测及综合评分分析结果则显示南阳菊花品质较好，非常适宜药用。

结论：

南阳从古至今皆为菊花优质产区，南阳菊花非常适宜药用，值得大力推广种植。

Abstract

Objective:

To study the origin of Nanyang Chrysanthemi Flos materia medica and its historical origin

in order to evaluate the quality of Nanyang Chrysanthemi Flos by HPLC method

and define the advantages of Nanyang Chrysanthemi Flos with the origin of Nanyang.

Method:

Records of Nanyang Chrysanthemi Flos in the " Chinese Medical Code" and related ancient documents were studied to explain the origin and application. The genetic relationship between Nanyang Chrysanthemi Flos and other pieces was revealed in ancient literatures. Then 8 chemical constituents in 14 batches of Chrysanthemi Flos were determined by HPLC multi-components quantitation

and the comprehensive weighted score analysis was performed based on the results. The HPLC fingerprints were established

and the similarity analysis and clustering analysis were made to comprehensive evaluation the quality of Nanyang Chrysanthemi Flos and define the genetic relationship between Nanyang and other pieces at the chemical composition level.

Result:

The results of the herbal textual research show that Nanyang Chrysanthemi Flos spread from place to place since the Han dynasty

and impact many medicinal chrysanthemums of later generations. HPLC fingerprints similarity and cluster analysis also indicated the genetic relationship between Nanyang Chrysanthemi Flos and other species at the chemical level. The comprehensive score analysis results show that Nanyang Chrysanthemi Flos is of good quality and very suitable for medicinal purposes.

Conclusion:

Nanyang has been a quality production area of Chrysanthemi Flos since ancient times to present. Nanyang Chrysanthemi Flos is very suitable for medicinal purposes and worthy of promotion.

关键词

Keywords

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