Correlation Between Color and Contents of Water and 5-Hydroxymethylfurfural in Ginseng Radix et Rhizoma Rubra

Cui WU; Liang XU; Yu-cui MA; Rui-qi LI; Zhi-mao CHAO

doi:10.13422/j.cnki.syfjx.20191615

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Correlation Between Color and Contents of Water and 5-Hydroxymethylfurfural in Ginseng Radix et Rhizoma Rubra

Resource and Quality Evaluation | 更新时间：2021-02-09

- Correlation Between Color and Contents of Water and 5-Hydroxymethylfurfural in Ginseng Radix et Rhizoma Rubra
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 25, Issue 20, Pages: 136-140(2019)
- 作者机构：
  
  中国中医科学院　中药研究所，国家中药材产业技术体系贮藏与包装岗位，北京　 100700
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20191615
  CLC： R284.2; R289; R22; R2-031
- Received：19 December 2018，
  
  Published Online：09 May 2019，
  
  Published：20 October 2019
- 稿件说明：
移动端阅览
Cui WU, Liang XU, Yu-cui MA, et al. Correlation Between Color and Contents of Water and 5-Hydroxymethylfurfural in Ginseng Radix et Rhizoma Rubra[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(20): 136-140.
DOI：

Cui WU, Liang XU, Yu-cui MA, et al. Correlation Between Color and Contents of Water and 5-Hydroxymethylfurfural in Ginseng Radix et Rhizoma Rubra[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(20): 136-140. DOI： 10.13422/j.cnki.syfjx.20191615.

摘要

目的：

探讨不同红参样品的色泽与水分和5-羟甲基糠醛(5-HMF)含量的相关性。

方法：

以白纸为背景日光下观察色泽；采用色差仪测定色度值，并计算色差值；采用烘干法测定水分；建立高效液相色谱法(HPLC)测定5-HMF的含量；采用Spearman和Pearson系数进行相关性分析。

结果：

红参的色泽呈黄白、土黄、棕黄色。色差仪测定和计算的

，

ΔE

有一定的范围，可以体现红参色泽。水分在4.02%～8.31%，符合2015年版《中国药典》的规定。5-HMF的含量从低于检测限(1.985×10

－4

μg)到78.97 μg·g

－1

。相关性分析结果认为，

，

和

ΔE

值均与水分含量存在极显著的相关性，即色泽越深水分含量越高；而与5-HMF的含量无显著相关性。

结论：

作为炮制品的红参，其色泽的差异与其中的水分含量有关，而与中药材中普遍存在的色泽与5-HMF含量相关的现象不一致，说明药材经炮制后色泽的深浅与药材本身色泽变化的原因具有本质区别。因此，控制水分含量，对于保证红参色泽的稳定具有重要意义。该文应用色差仪对红参进行色泽的测定，系统地测定了其中5-HMF的含量，并提出水分含量对红参色泽的影响。

Abstract

Objective:

To explore the correlation between colors and contents of water and 5-hydroxymethylfurfural (5-HMF) in Ginseng Radix et Rhizoma Rubra (GRRR).

Method:

The colors were observed under sunlight on a sheet of white paper. The chroma value and color difference were determined and calculated by a colorimeter. Water content was determined by the oven-drying method. An HPLC method was established and used to determine the content of 5-HMF. The correlation was analyzed by the Spearman and Pearson analysis.

Result:

The colors of GRRR were yellowish-white

ocher-yellow

and yellowish-brown. The values of

and

ΔE

had a certain range

and could reflect the colors of GRRR. The content of water ranged from 4.01%to 8.31%and was in accordance with the requirement the

Chinese Pharmacopoeia

. The content of 5-HMF ranged from below the limit of detection (1.985×10

-4

μg) to 78.97 μg·g

-1

. The results of correlation analysis shows significant correlations between

ΔE

values and water content

that is to say

the deeper the color was

the higher the content of water was

but with no significant correlation with 5-HMF content.

Conclusion:

The color of processed GRRR was related to water content but not related to 5-HMF content

which was not consistent with the correlation between color and 5-HMF content that generally existed in a series of raw Chinese medicinal materials. It indicated an essential difference between the color shade of processed Chinese medicinal materials and the cause of color change of raw Chinese medicinal materials. Therefore

it was significant to control water content for ensuring the stability of GRRR. This study determined the colors of GRRR by a colorimeter

systematically determined 5-HMF content

and proposed the effect of water contents on the color of GRRR.

关键词

Keywords

references

国家药典委员会．中华人民共和国药典．一部 [M]．北京：中国医药科技出版社， 2015 ： 154 ．

刘丹，濮社班，钱士辉，等．中国红参化学成分的研究 [J]．中国中药杂志， 2011 ， 36 ( 4 )： 462 - 464 ．

李帅坪，黄鑫，张勇，等．红参皂苷组分对大鼠血浆中神经化学物质的影响 [J]．中草药， 2017 ， 48 ( 14 )： 2918 - 2924 ．

黄宝亮，丁传波，王佳奇，等．红参中精氨酸双糖苷对小鼠的抗疲劳作用 [J]．吉林大学学报：医学版， 2017 ， 43 ( 5 )： 897 - 902 ．

黄丽，靳庆霞．红参水提物对哮喘气道炎症小鼠的治疗作用及其机制研究 [J]．医学研究杂志， 2017 ， 46 ( 11 )： 161 - 164 ．

Hidayat W , QI Y , Jang J H , et al . Color change and consumer preferences towards color of heat-treated Korean white pine and royal paulownia woods [J]. J Korean Wood Sci Tech , 2017 , 45 ( 2 ): 213 - 222 .

吕新广，赵美京． CIELAB色度空间的均匀性研究 [J]．郑州大学学报：理学版， 2002 ， 34 ( 1 )： 69 - 73 ．

Fallico B , Arena E , Zappala M . Degradation of 5-hydroxymethylfurfural in honey [J]. J Food Sci , 2008 , 73 ( 9 ): C625 - 631 .

LI M M , WU L Y , ZHAO T , et al . The protective role of 5-hydroxymethyl-2-furfural (5-HMF) against acute hypobaric hypoxia [J]. Cell Stress Chaperon , 2011 , 16 ( 5 ): 529 - 537 .

ZHAO L , CHEN J , SU J , et al . In vitro antioxidant and antiproliferative activities of 5-hydroxymethylfurfural [J]. J Agric Food Chem , 2013 , 61 ( 44 ): 10604 - 10611 .

Janzowski C , Glaab V , Samimi E , et al . 5-Hydroxymethylfurfural: assessment of mutagenicity, DNA-damaging potential and reactivity towards cellular glutathione [J]. Food Chem Toxicol , 2000 , 38 ( 9 ): 801 - 809 .

Uubricht R J , Northup S J , Thomas J A . A review of 5-hydroxymethylfurfural (HMF) in parenteral solutions [J]. Fundam Appl Toxicol , 1984 , 4 ( 5 ): 843 - 853 .

Somoza V . Five years of research on health risks and benefits of Maillard reaction products: an update [J]. Mol Nutr Food Res , 2005 , 49 ( 7 ): 663 - 672 .

Durling L J , Busk L , Hellman B E . Evaluation of the DNA damaging effect of the heat-induced food toxicant 5-hydroxymethylfurfural (HMF) in various cell lines with different activities of sulfotransferases [J]. Food Chem Toxicol , 2009 , 47 ( 4 ): 880 - 884 .

吴翠，马玉翠，晋文慧，等．简易库和冷藏库贮藏中牛膝理化指标的月动态变化研究 [J]．中国药学杂志， 2017 ， 52 ( 24 )： 2151 - 2156 ．

于莉，吴晓毅，梁曜华，等．山萸肉不同仓储时间与5-羟甲基糠醛含量的相关性研究 [J]．中国中医药信息杂志， 2015 ， 22 ( 6 )： 95 - 98 ．

吴翠，唐春风，马玉翠，等．不同色泽龙眼肉中5-羟甲基糠醛的含量测定及相关性分析 [J]．时珍国医国药， 2018 ， 29 ( 1 )： 42 - 44 ．

吴翠，刘超，巢志茂．大枣色泽与5-羟甲基糠醛含量相关性分析 [J]．中国中医药信息杂志， 2016 ， 23 ( 8 )： 83 - 86 ．

吴翠，高岳瑞，巢志茂，等．五味子中5-羟甲基糠醛含量与仓储和色泽的相关性 [J]．中国实验方剂学杂志， 2016 ， 22 ( 15 )： 24 - 27 ．

孙文，巢志茂，王淳，等． HPLC对市售瓜蒌中5-羟甲基糠醛的含量测定 [J]．中国实验方剂学杂志， 2012 ， 18 ( 18 )： 73 - 76 ．

初红梅，曲桂武，戴胜军，等．红参中美拉德反应产物研究 [J]．中国实验方剂学杂志， 2014 ， 20 ( 9 )： 86 - 89 ．

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