Determination and Analysis of Heavy Metals of Paridis Rhizoma from Different Localities and Pieces

Ruo-shi LI; Hui-qiong YUAN; Fei-ya ZHAO; Ai-en TAO; Bao-zhong DUAN; Kan HU; Cong-long XIA

doi:10.13422/j.cnki.syfjx.20191660

您当前的位置：

首页 >

文章列表页 >

Determination and Analysis of Heavy Metals of Paridis Rhizoma from Different Localities and Pieces

Topic of Research on Medicinal Materials Resources in Yunnan | 更新时间：2021-02-09

- Determination and Analysis of Heavy Metals of Paridis Rhizoma from Different Localities and Pieces
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 25, Issue 15, Pages: 30-36(2019)
- 作者机构：
  
  大理大学　药学与化学学院，云南　大理　 671000
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20191660
  CLC： R284.2; R289; R22; R2-031
- Received：31 October 2018，
  
  Published Online：29 May 2019，
  
  Published：05 August 2019
- 稿件说明：
移动端阅览
Ruo-shi LI, Hui-qiong YUAN, Fei-ya ZHAO, et al. Determination and Analysis of Heavy Metals of Paridis Rhizoma from Different Localities and Pieces[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(15): 30-36.
DOI：

Ruo-shi LI, Hui-qiong YUAN, Fei-ya ZHAO, et al. Determination and Analysis of Heavy Metals of Paridis Rhizoma from Different Localities and Pieces[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(15): 30-36. DOI： 10.13422/j.cnki.syfjx.20191660.

摘要

目的：

分析测定不同产地不同种类的重楼药材中的重金属含量，为重楼种植地区的选择和其重金属元素限量标准提供参考。

方法：

从云南省10个产地收集8种共39份重楼药材样品，采用微波消解-电感耦合等离子体原子发射光谱法(ICP-AES)测定重楼药材中的重金属砷(As)，铜(Cu)，汞(Hg)，镉(Cd)，铅(Pb)，铬(Cr)的含量，采用聚类分析，统计分析和主成分分析不同产地和种类对重金属含量累积特征进行分析。

结果：

六种重金属含量均符合《中医药-中药材重金属限量》ISO国际标准；按《药用植物及制剂进出口绿色行业标准》限量值标准，As，Cd，Pb的超标率为15.4%，5.1%，2.6%，Cu，Hg均符合相关要求。聚类分析，主成分分析可将样品按产地分为大理和昭通两类，统计分析结果表明产地对重金属含量的影响极显著，不同品种间差异较小。

结论：

该研究结果表明云南省各产区种植重楼的重金属含量基本符合相关标准，重楼药材的重金属含量差异主要表现为地域差异，为规范化种植重楼药材和其重金属含量限量标准的制定提供了理论依据。

Abstract

Objective:

To analyze and determine heavy metal content in Paridis Rhizoma from different genus and localities

in order to provide a reference for selecting cultivation areas and establishing the quality standard of Paridis Rhizoma of heavy metals content.

Method:

Microwave digestion method combined with inductively coupled plasma atomic emission spectrometry method (ICP-AES) method were applied to determine the contents of 6 heavy metals

i.e. As

Pb and Cr in 39 samples of Paridis Rhizoma of different genus and localities in Yunnan Province. Cluster analysis

statistical analysis and principal component analysis (PCA) were used to compare the differences of heavy metals contents in different localities and species.

Result:

The contents of six heavy metals in Paridis Rhizoma met the ISO international standard of

Heavy Metal Limit of Traditional Chinese Medicine

traditional Chinese Medicinal Materials

. Under the limited value standard of

Green Trade Standards of Importing Medicinal Plants and Preparations

the over-standard rate of heavy metal As was 15.4%

the excess rate of Cd was 5.1%

and the excess rate of Pb was 2.6%. The contents of Cu and Hg conformed to relevant requirements. Cluster analysis

statistical analysis and principal component analysis showed that for the same variety

differences in producing places had significant effects on heavy metal content

while differences in species had little effects.

Conclusion:

The results of this study indicated that the heavy metal content of

Paris

planted in and around Dali basically conformed to relevant standards. The differences of heavy metal content in

Paris

were mainly regional differences

which provided a theoretical basis for standardizing the cultivation of medicinal materials and formulating the limit standards of heavy metals for Paridis Rhizoma.

关键词

Keywords

references

国家药典委员会．中华人民共和国药典．一部 [M]．北京：中国医药科技出版社， 2015 ： 260 ．

赵飞亚，陶爱恩，夏从龙．基于国内专利结合资源、应用与开发现状的重楼发展策略探讨 [J]．中国中药杂志， 2018 ， 43 ( 2 )： 404 - 409 ．

李洪梅，孙建辉，康利平，等．重楼同属植物长柱重楼与药用重楼的药效学对比研究 [J]．中国中药杂志， 2017 ， 42 ( 18 )： 3461 - 3464 ．

张兰天，左予桐，高文远，等．云南重楼提取物及化学成分的抗肿瘤活性研究 [J]．中草药， 2007 ， 38 ( 3 )： 422 - 424 ．

黄圆圆，刘大会，彭华胜，等． 15种重楼属植物中8种甾体皂苷的含量测定 [J]．中国中药杂志， 2017 ， 42 ( 18 )： 3443 - 3451 ．

武珊珊，高文远，段宏泉，等．重楼化学成分和药理作用研究进展 [J]．中草药， 2004 ， 35 ( 3 )： 110 - 113 ．

张朝阳，赵庭周．重楼资源再生策略及其关键技术环节探讨 [J]．中草药， 2009 ， 40 ( 2 )： 319 - 323 ．

韩小丽，张小波，郭兰萍，等．中药材重金属污染现状的统计分析 [J]．中国中药杂志， 2008 ， 33 ( 18 )： 2041 - 2048 ．

邹亮，周浓，杨颖，等．不同产地滇重楼中重金属含量的湿法消解-原子荧光光度法测定 [J]．时珍国医国药， 2010 ， 21 ( 4 )： 1014 - 1015 ．

张静，丁博，肖国生，等．三峡库区栽培重楼药材和土壤中营养元素的相关性分析 [J]．中国实验方剂学杂志， 2016 ， 22 ( 4 )： 32 - 38 ．

周浓，张杰，郭冬琴，等．三峡库区栽培重楼中重金属元素的含量与评价 [J]．环境化学， 2015 ， 34 ( 9 )： 1758 - 1760 ．

杨敏，张杰，沈昱翔，等．滇重楼与丛枝菌根的共生对重金属元素吸收的影响 [J]．环境化学， 2018 ， 37 ( 4 )： 860 - 870 ．

周浓，张德伟，郭冬琴，等．菌根真菌对人工栽培滇重楼重金属元素的影响 [J]．中成药， 2014 ， 36 ( 12 )： 2583 - 2586 ．

朱建成，尚毅，刘咏梅，等．重楼植物中无机元素研究进展 [J]．天津中医药， 2018 ， 35 ( 2 )： 153 - 156 ．

International Organization for Standardization . ISO 18664: 2015 Traditional Chinese Medicine-Determination of heavy metals in herbal medicines used in Traditional Chinese Medicine [S/OL]. https://www.iso.org/standard/63150.html .

药用植物及制剂进出口绿色行业标准 [J]．中国农业信息快讯， 2002 ( 8 )： 28 - 29 ．

中华人民共和国国家和卫生计划委员会，国家食品药品监督管理总局． GB 2762-2012.食品安全国家标准食品中污染物限量 [S]． 2012 ．

秦双双，黄静雯，袁媛，等．中药材重金属元素及其与指标性成分相关性分析 [J]．中国实验方剂学杂志， 2018 ， 24 ( 6 )： 66 - 70 ．

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Determination of Harmful Elements in Cervi Cornus Colla Based on Microwave Digestion and ICP-AES Technology

Determination of Harmful Elements Pb,As,Cd,Hg,Cuin Reduning Injection by ICP-MS

Investigation of Heavy Metals Content in Nine Kinds of Commercial Traditional Chinese Medicines

Spectrum-effect Relationship of Anti-hepatoma Activity from 3 Kinds of Genus Paris Based on Cluster Analysis and Grey Relational Analysis

Related Author

SHI Yan

XIAO Xin-yue

WEI Feng

XIONG Jing

MA Shuang-cheng

LIN Rui-chao

HU Jun-hua

WANG Jin-ling

Related Institution

College of Tourism and Culture, Yunnan University

The First People's Hospital of Yiliang

College of Pharmacy and Chemistry, Key Laboratory of Universities in Yunnan Province on Development of Genuine Medicinal Materials Resources in Western Yunnan, Dali University

National Plarmaceutical Engineering Cenrer for Preparation in Chinese Herbal Medicine

Jiangxi University of Traditional Chinese Medicine

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰