Comparison of Volatile Oil of Domestic and Foreign Panacix Quinquefolii Radix by HS-SPME/GC-MS

Yu SI; Yun-he LIU; Zhong-yao WANG; Jin-ping LIU; Ping-ya LI; Yu-feng JIAO

doi:10.13422/j.cnki.syfjx.20191815

您当前的位置：

首页 >

文章列表页 >

Comparison of Volatile Oil of Domestic and Foreign Panacix Quinquefolii Radix by HS-SPME/GC-MS

Resource and Quality Evaluation | 更新时间：2021-02-09

- Comparison of Volatile Oil of Domestic and Foreign Panacix Quinquefolii Radix by HS-SPME/GC-MS
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 25, Issue 18, Pages: 130-138(2019)
- 作者机构：
  
  吉林大学　药学院　天然药物研究中心，长春　 130021
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20191815
  CLC： R284.1; R282.6; R22; R243
- Received：23 April 2019，
  
  Published Online：10 July 2019，
  
  Published：20 September 2019
- 稿件说明：
移动端阅览
Yu SI, Yun-he LIU, Zhong-yao WANG, et al. Comparison of Volatile Oil of Domestic and Foreign Panacix Quinquefolii Radix by HS-SPME/GC-MS[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(18): 130-138.
DOI：

Yu SI, Yun-he LIU, Zhong-yao WANG, et al. Comparison of Volatile Oil of Domestic and Foreign Panacix Quinquefolii Radix by HS-SPME/GC-MS[J]. Chinese journal of experimental traditional medical formulae, 2019, 25(18): 130-138. DOI： 10.13422/j.cnki.syfjx.20191815.

摘要

目的：

对不同产地与不同年限的西洋参的挥发性化学成分进行测定分析，为西洋参的进一步开发和利用提供理论依据。

方法：

采用顶空固相微萃取(HS-SPME)技术结合气相色谱-质谱联用法(GC-MS)对西洋参的挥发性成分进行提取、分析与鉴定，采用色谱峰面积归一化法确定各成分的相对含量。

结果：

西洋参样品中共鉴定出151种成分，包括烃类99种、醇酚类21种、醛类7种，酮类8种，酯类1种，杂环类及其他成分15种。3年生吉林白山产西洋参根中鉴定出68种成分，质量分数98.27%；4年生吉林白山产西洋参根中鉴定出67种成分，质量分数98.79%；3年生美国产西洋参根中鉴定出65种成分，质量分数95.81%；4年生美国产西洋参根中鉴定出63种成分，质量分数99.67%。4个西洋参样品的挥发油成分中的特有成分分别为24，23，19和23种，共有成分为16种。

结论：

不同产地的不同年限的西洋参的挥发性化学成分的含量和组成存在很大差异，该实验结果为未来西洋参药材质量评价研究以及资源的充分合理开发利用提供借鉴。

Abstract

Objective:

To determine the volatile chemical constituents of Panacix Quinquefolii Radix of different origins and different growth years

in order to provide the theoretical basis for the further development and utilization of Panacix Quinquefolii Radix .

Method:

Headspace solid phase microextraction (HS-SPME) combined with gas chromatography-mass spectrometry (GC-MS) was used to extract

analyze and identify the volatile constituents of Panacix Quinquefolii Radix . The chromatographic peak area normalization method was used to determine the relative amount of ingredients.

Result:

A total of 151 compounds were identified in Panacix Quinquefolii Radix samples

including 99 hydrocarbons

21 alcohol phenols

7 aldehydes

8 ketones

1 ester

15 heterocyclics and other compounds. Totally 68 kinds of compounds were identified in the roots of three-year-old Jilin Baishan

and the mass fraction accounted for 98.27%

67 compounds were identified in the roots of four-year-old Jilin Baishan

and the mass fraction accounted for 98.79%

65 compounds were identified in 3-year-old Panacix Quinquefolii Radix root

and the mass fraction accounted for 95.81%

and 63 compounds were identified in 4-year-old Panacix Quinquefolii Radix root

and the mass fraction accounted for 99.67%. The specific components of the volatile oil components of the four Panacix Quinquefolii Radix samples were 24

and 23

respectively

and the total composition was 16 species.

Conclusion:

The content and composition of volatile chemical constituents of Panacix Quinquefolii Radix of different origins are very different. This experiment provides a reference for the future quality evaluation of Panacix Quinquefolii Radix medicinal materials

rational development and utilization of resources.

关键词

Keywords

references

国家药典委员会．中华人民共和国药典．一部 [M]．北京：中国医药科技出版社， 2015 ： 131 ．

何晓燕，王兵，朱卫兵．西洋参的化学成分与药理作用 [J]．益寿宝典， 2017 ， 5 ( 32 )： 56 - 57 ．

ZHUO D R , QUE H T , ZHANG N , et al . In vitro dissolution rate of ginsenoside Rb1 in superfine powder of wild Panacis Quinquefolii Radix [J]. Drug Eval Res , 2013 , 36 : 374 - 376 .

MAO J , Juan M M , Tom C , et al . American ginseng acutely regulates contractile function of rat heart [J]. Fronti Pharmacol , 2014 , 5 : 43 .

Assinewe A V , Baum R B , Gagnon D , et al . Phytochemistry of wild populations of Panax quinquefolius L. (North American ginseng) [J]. J Agric Food Chem , 2003 , 51 ( 16 ): 4549 - 4553 .

王倩．糖脂平方治疗2型糖尿病胰岛素抵抗(气阴两虚兼痰瘀证)的临床研究 [D]．兰州：甘肃中医药大学， 2016 ．

Singh R K , Lui E , Wright D , et al . Alcohol extract of North American ginseng (Panax quinquefolius)reduces fatty liver, dyslipidemia, and other complications of metabolic syndrome in a mouse model [J]. Can J Physiol Pharmacol , 2017 , 95 : 1046 - 1057 .

Mucalo I , Jovanovski E , Raheli D , et al . Effect of American ginseng (Panax quinquefolius L.) on arterial stiffness in subjects with type-2 diabetes and concomitant hypertension [J]. J Ethnopharmacol , 2013 , 150 : 148 - 153 .

Dougherty U , Mustafi R , WANG Y , et al . American ginseng suppresses Western dietpromoted tumorigenesis in model of inflammation-associated colon cancer: role of EGFR [J]. BMC Complementary and Alternative Medicine , 2011 , 11 : 1 - 11 .

Sandra C M , Danielle D , Jacqueline J S . Extract of North American ginseng (Panax Quinquefolius), administered to leukemic, juvenile mice extends their life Span [J]. J Complement Inteqr Med , 2011 , 8 : 1553 - 3840 .

唐艳，闫述模，汪静静，等．基于UPLC及多成分分析的西洋参质量评价 [J]．中国中药杂志， 2016 ， 41 ( 9 )： 1678 - 1684 ．

张丹，郑开颜，吴兰芳，等．西洋参药材的质量特征与商品规格的相关性分析 [J]．中国中药杂志， 2016 ， 41 ( 18 )： 3329 - 3335 ．

郑友兰，张崇禧，李向高，等．国产西洋参与进口西洋参的比较研究一西洋参中挥发油成分的分析 [J]．药学学报， 1989 ， 24 ( 2 )： 118 - 121 ．

常宇桐，罗云敬，钱承敬，等．顶空固相微萃取-气相色谱质谱法测定馥郁香型白酒中的挥发性香气成分 [J]．食品安全质量检测学报， 2018 ， 9 ( 17 )： 4618 - 4627 ．

吴稚冰，马胜林． β-榄香烯抗肿瘤作用的研究进展 [J]．中华中医药学刊， 2011 ， 29 ( 10 )： 2255 - 2257 ．

谢小洋，冯永忠，王得祥． 5种园林树木挥发性成分分析 [J]．西北农林科技大学学报：自然科学版， 2016 ， 44 ( 7 )： 146 ．

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Age Discrimination Based on Volatile Components of Arisaema Cum Bile

HS-SPME-GC-MS Analysis on Changes in Volatile Components in Raphani Semen Before and After Stir-frying

HS-SPME-GC-MS Analysis on Volatile Components of Different Varieties and Different Parts of

Analysis of Volatile Component Changes During Processing of Gardeniae Fructus Carbonisata by HS-GC-IMS Combined with Chemometrics

Analysis of Dynamic Change Patterns of Color and Composition During Fermentation of Myristicae Semen Koji

Related Author

HE Jia

NAN Tiegui

LIU Tianrui

ZHAO Yuyang

LIU Ying

JIN Yan

YUAN Yuan

XIA Qing-song

Related Institution

School of Traditional Chinese Medicine（TCM）， Guangdong Pharmaceutical University

State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs， National Resource Center for Chinese Materia Medica， China Academy of Chinese Medical Sciences

Institute of TCM Health Industry，China Academy of Chinese Medical Sciences

Beijing Shuangqiao Yanjing Chinese Medicine Pieces Factory

Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰