Based on the pharmacovigilance thoughts of Chinese medicine of cognition

application

prevention and rescue of drug toxicity

to sort out the pharmacovigilance information in representative herbal works of the Ming dynasty

and to analyze the characteristics of the pharmacovigilance thoughts of the Ming dynasty

so as to provide reference for rational drug use in modern clinical practice. Taking

Bencao Pinhui Jingyao

Bencao Gangmu

Paozhi Dafa

Bencao Shengya Banjie

Bencao Mengquan

as the blueprints

and taking the traditional Chinese medicines in these books as the research objects

the text information was extracted from the four aspects of drug identification

drug use

drug prevention and detoxification

and the idea of pharmacovigilance was summarized. In Ming dynasty

pharmacovigilance had a systematic understanding

and cognition of drug toxicity was clear in identifying poison and correcting the mistakes of predecessors

in the aspects of using and preventing poisons

the use of poisons was prominent

the compatibility and process of poisons were emphasized

and the methods and mechanism of poison relief were clear in detoxification. Ming dynasty has initially formed the whole pharmacovigilance theoretical frame of cognition

application

prevention and rescue of drug toxicity

which has certain guiding and reference significance for modern clinical rational drug use.