Research Progress on Chemical Constituents and Pharmacological Effects of Piperis Fructus

Lan YU; Zheng-yi HAO; Xiao-lu HU; Zong-xi CAO; Bing CAO; Xia WU

doi:10.13422/j.cnki.syfjx.20192149

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Research Progress on Chemical Constituents and Pharmacological Effects of Piperis Fructus

Review | 更新时间：2021-02-09

- Research Progress on Chemical Constituents and Pharmacological Effects of Piperis Fructus
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 26, Issue 6, Pages: 234-242(2020)
- 作者机构：
  
  1.首都医科大学　中医药学院，北京　 100069
  2.海南省农业科学院　畜牧兽医研究所，海口　 571100
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20192149
  CLC： R22; R28; R96; R914; R24; G353.11
- Received：09 May 2019，
  
  Published Online：19 July 2019，
  
  Published：20 March 2020
- 稿件说明：
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Lan YU, Zheng-yi HAO, Xiao-lu HU, et al. Research Progress on Chemical Constituents and Pharmacological Effects of Piperis Fructus[J]. Chinese journal of experimental traditional medical formulae, 2020, 26(6): 234-242.
DOI：

Lan YU, Zheng-yi HAO, Xiao-lu HU, et al. Research Progress on Chemical Constituents and Pharmacological Effects of Piperis Fructus[J]. Chinese journal of experimental traditional medical formulae, 2020, 26(6): 234-242. DOI： 10.13422/j.cnki.syfjx.20192149.

摘要

胡椒为胡椒科胡椒属植物胡椒的干燥近成熟或成熟果实，既是重要的香辛料，也是一味传统的中药，在世界范围内广泛应用，具有温中散寒、下气、消痰的功效。胡椒中主要含有以胡椒碱为主的酰胺类生物碱和以单萜、倍半萜类化合物为主的挥发油成分，具有抗癌、抗氧化、抗菌、抗炎、降糖、抗抑郁等广泛的生物活性。笔者通过查阅、整理国内外近5年有关胡椒的文献资料，对胡椒果实、梗、叶、花等不同部位所含化学成分以及药理作用的相关研究进行总结和分析，发现其作为药食同源的中药具有良好的药物开发潜力，可为胡椒的后续研究和深度利用提供参考。

Abstract

Piperis Fructus is the dried nearly ripe or ripe fruit of Piperaceae

which is an important spice material and a traditional Chinese medicine (TCM)

it is widely used in the world. It is recorded to possess the efficacy of warming spleen and stomach for dispelling cold

depressing Qi and dissolving phlegm. Piperis Fructus mainly contains amide alkaloids with piperine as the main ingredient and volatile oil dominated by monoterpenoids and sesquiterpenoids

which have a wide range of biological activities

such as anti-cancer

anti-oxidation

anti-inflammatory

etc. By referring to relevant papers at home and abroad

the researches on chemical compositions from different parts and pharmacological effects of Piperis Fructus in recent 5 years were summarized and analyzed. It was found that Piperis Fructus has great potential for drug development as a TCM with homology of medicine and food

which can provide a reference for further research and comprehensive utilization of Piperis Fructus.

关键词

Keywords

references

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