Relationship Between Characters and Main Components of Chelidonii Herba Pieces

Rui-hai LI; Sheng-nan ZHAO; Tian-zhu JIA

doi:10.13422/j.cnki.syfjx.20192411

您当前的位置：

首页 >

文章列表页 >

Relationship Between Characters and Main Components of Chelidonii Herba Pieces

Resource and Quality Evaluation | 更新时间：2021-04-16

- Relationship Between Characters and Main Components of Chelidonii Herba Pieces
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 26, Issue 2, Pages: 144-148(2020)
- 作者机构：
  
  辽宁中医药大学　药学院，辽宁大连　 116600
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20192411
  CLC： R289; R284.1; R22; R2-031
- Received：24 February 2019，
  
  Published Online：04 September 2019，
  
  Published：20 January 2020
- 稿件说明：
移动端阅览
Rui-hai LI, Sheng-nan ZHAO, Tian-zhu JIA. Relationship Between Characters and Main Components of Chelidonii Herba Pieces[J]. Chinese journal of experimental traditional medical formulae, 2020, 26(2): 144-148.
DOI：

Rui-hai LI, Sheng-nan ZHAO, Tian-zhu JIA. Relationship Between Characters and Main Components of Chelidonii Herba Pieces[J]. Chinese journal of experimental traditional medical formulae, 2020, 26(2): 144-148. DOI： 10.13422/j.cnki.syfjx.20192411.

摘要

目的：

确定白屈菜饮片的性状与主要成分间关系分析。

方法：

采用HPLC，测定样品主要成分，采用感观评定法，评价白屈菜的性状，采用相关度公式计算性状与成分的相关度。

结果：

所制定的HPLC法能够测定白屈菜碱等6个成分的含量，结合感观评定结果，性状与成分具有一定的相关性。性状描述“有的可见白粉，有的具白色柔毛，有时可见黄色小花”等与总碱相似度非常低，说明这些性状与总碱含量没有关系。其中“茎干瘪中空”的描述和总碱含量的相似度高，说明茎量的多少关系到了总碱含量的高低。而“叶多破碎”的性状描述和总碱的相似度是较高的负相关，说明叶相对多(或破碎的较多)的话，总碱含量要少，反之则含量相对较高。

结论：

所建立的HPLC含量测定方法，简单易行，性状与成分具有一定的相关性。该研究给白屈菜性状描述进行客观量化，并与白屈菜主要成分进行关联，进而从性状外观上初步判断白屈菜质量，为白屈菜在市场中凭经验鉴定提供一定的理论根据，也为其他中药的性状研究提供了一个思路。

Abstract

Objective:

To determine the relationship between the characters and the main components of Chelidonii Herba pieces.

Method:

The main components of the samples were determined by HPLC

and the characters of Chelidonii Herba Pieces were evaluated by sensory evaluation. The correlation between the characters and components was calculated by correlation formula.

Result:

The content of 6 components

such as chelidonine

was determined by HPLC. Based on the result of sensory evaluation

there was a certain correlation between the characters and the components. Character descriptions that " some have visible white powder

some have white pubescence

and sometimes they have visible yellow florets" had a very low similarity with total alkali

indicating that these characters and total alkali content was not related. The similarity between the description of " hollow stem" had a high similarity with total alkali content

indicating that the amount of stem was related to the total alkali content. The character description of " more broken leaves" was negatively correlated with total alkaloids in the similarity

which indicated that the content of total alkaloids was less when there were more leaves(or more broken leaves)

otherwise

the content of total alkaloids was relatively higher.

Conclusion:

The established HPLC method is simple and feasible. This study objectively quantifies the descriptions of Chelidonii Herba pieces characters

correlates them with the main components of Chelidonii Herba pieces

and then preliminarily judges the quality of Chelidonii Herba pieces according to the appearance of the characters

which provides a theoretical basis for the identification of Chelidonii Herba pieces in the market by experience

and ideas for the study of the characters of other traditional Chinese medicines.

关键词

Keywords

references

国家中医药管理局．《中华本草》编委会．中华本草．第9卷 [M]．上海：上海科学技术出版社， 1999 ： 616 .

国家药典委员会．中华人民共和国药典．一部 [M]．北京：中国医药科技出版社， 2015 ： 109 .

冯泓瑞，黄松，陈玲玲，等．白屈菜红碱、血根碱单体的分离和鉴定 [J]．中国实验方剂学杂志， 2013 ， 19 ( 14 )： 36 - 38 .

确生，王志波，李成思，等．响应面法优化斑花黄堇中总生物碱的提取工艺 [J]．中国现代应用药学， 2017 ， 34 ( 3 )： 358 - 362 .

夏成才，肖玉良，王彩云，等．白屈菜总生物碱的提取工艺研究 [J]．时珍国医国药， 2010 ， 21 ( 12 )： 3216 - 3217 .

鲁文静，罗世恒，陈世忠．白屈菜中多种生物碱含量的高效液相色谱法测定 [J]．时珍国医国药， 2013 ， 24 ( 3 )： 601 - 603 .

杨志欣，王海威，张文君，等．苦参总黄酮含量测定方法的优化 [J]．中成药， 2017 ， 39 ( 5 )： 946 - 951 .

李瑞海，冯琳，马欣悦，等．脂肪油和总二萜含量与柏子仁质量的相关性分析 [J]．中国实验方剂学杂志， 2015 ， 21 ( 12 )： 9 - 11 .

王羡一，李瑞海，贾天柱．均质法联合超滤膜纯化侧柏叶黄酮成分的方法初探 [J]. 中国药师， 2017 ， 20 ( 4 )： 661 - 663，667 .

李静，田芳，李美艳，等．白屈菜提取物中生物碱的镇痛抗炎作用研究 [J]．中国实验方剂学杂志， 2013 ， 19 ( 8 )： 262 - 265 .

王雪，刘洪章，刘树英，等．响应面法优化白屈菜根中白屈菜碱提取工艺的研究 [J]．黑龙江畜牧兽医， 2016 ，( 8上 )： 201 - 204 .

赵胜男，李瑞海，贾天柱．响应面法优化白屈菜中总生物碱酸水提取的工艺 [J]．中国药师， 2019 ， 22 ( 3 )： 541 - 545 .

冯慧，赵娅，王小艳，等．小檗皮总生物碱取物的大孔树脂纯化工艺与质量标准考察 [J]．中国实验方剂学杂志， 2019 ， 25 ( 16 )： 97 - 103 .

万超，于定荣，刘颖，等．醋延胡索饮片颜色与其内在质量的相关性分析 [J]．中国实验方剂学杂志， 2019 ， 25 ( 12 )： 145 - 150 .

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Simultaneous Determination of Eleven Major Alkaloids in Corydalis Rhizoma by RP-HPLC

Simultaneous Determination of Four Active Components in Tong'an Injection by HPLC Under Multiple UV Wavelengths

Comparison of Wild and Cultivated Bupleurum chinense Based on Traditional Quality Evaluation

Comparison of Wild and Cultivated Codonopsis pilosula Based onTraditional Quality Evaluation

Comparison of Wild and Cultivated Paeoniae Radix Rubra Based on Traditional Quality Evaluation

Related Author

YANG Min

LI Chun

FENG Wei-hong

ZHANG Yong-xin

LIN Li-mei

CHEN An-jia

YANG Li-xin

LIN Xia

Related Institution

National Resource Center for Chinese Materia Medica，State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs， China Academy of Chinese Medical Sciences

Hubei Provincial Key Laboratory of Selenium Resources Research and Biological Application， Hubei Minzu University

Infinitus（China） Co. Ltd.

Institute of TCM Health Industry，China Academy of Chinese Medical Sciences

Tianjin University of Traditional Chinese Medicine（TCM）

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰