YUE Ping,TANG Shi-huan,YU Huan,et al.Analysis of Pathogenesis and Prescription Formulating Principle of Traditional Chinese Medicine Prevention and Treatment Plan for COVID-19[J].Chinese Journal of Experimental Traditional Medical Formulae,2020,26(14):13-19.
YUE Ping,TANG Shi-huan,YU Huan,et al.Analysis of Pathogenesis and Prescription Formulating Principle of Traditional Chinese Medicine Prevention and Treatment Plan for COVID-19[J].Chinese Journal of Experimental Traditional Medical Formulae,2020,26(14):13-19. DOI: 10.13422/j.cnki.syfjx.20200842.
Analysis of Pathogenesis and Prescription Formulating Principle of Traditional Chinese Medicine Prevention and Treatment Plan for COVID-19
Since the outbreak of coronavirus disease 2019 (COVID-19)
the health authorities in various regions have formulated a group of traditional Chinese medicine (TCM) diagnosis and treatment programs based on the consensus analysis of etiology and pathogenesis of TCM experts
and recommended the guiding prescriptions for different syndromes in three stages of prevention
treatment and recovery. In order to effectively summarize the understanding of the pathogenesis of each scheme and the rules of the formulation of various prescriptions
based on 49 TCM prevention and treatment plans issued by the health administration departments
308 TCM prescriptions were sorted by stages (151 prescriptions in the treatment period
118 prescriptions in the prevention period and 39 prescriptions in the recovery period). The 2019-nCoV pneumonia prescriptions was further processed by using TCM inheritance platform system. The common syndromes and the frequency of commonly used Chinese medicines were summed up. The commonly used drug pairs and combinations in different stages were extracted
and their association rules were analyzed. The rules of the Chinese herbal prescription for COVID-19 were preliminarily summarized. During the treatment period
the main syndrome types are inner blocking causing collapse
epidemic toxin in the lung
cold dampness in the lung and toxic heat in the lung
involving 187 kinds of herbs
29 kinds of herbs with single taste frequency more than 20 times.Armeniacae Semen Amarum is the most frequently used
Gypsum Fibrosum-Armeniacae Semen Amarum is the most frequently used drug-pair
the core formula is Maxing Shigan Tang
and the main pathogenesis is cold
wet and heat. There is no unified syndrome type in the prevention period
involving 119 herbs in total. There are 13 kinds of herbs with single taste frequency more than 20 times. The most frequently used is Astragali Radix. The most frequently used medicine pair is Astragali Radix-Saposhnikoviae Radix. The core formula is Yupingfeng San
and the main pathogenesis is Qi deficiency. During the recovery period
the main syndromes are deficiency of lung and spleen Qi deficiency and Qi and Yin deficiency
involving 113 herbs
12 kinds of herbs with single taste frequency more than 10 times
Poria with the highest frequency of use
Citri Reticulatae Pericarpium-Poria with the highest frequency of drug pairing
Erchentang and Shengmaiyin with the main pathogenesis of deficiency of spleen Qi and Yin. The purpose of this study is to provide multiple references for strengthening clinical precise treatment
improving the effect of TCM treatment and promoting the management of TCM prevention and control resources.