Quality Regionalization and Environmental Impact Factors Analysis Based on Main Active Ingredients of Stephaniae Tetrandrae Radix

Fan YANG; Meng-li WU; Hui GAO; Qiu-mei HE; Yang-jiao XIE

doi:10.13422/j.cnki.syfjx.20201112

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Quality Regionalization and Environmental Impact Factors Analysis Based on Main Active Ingredients of Stephaniae Tetrandrae Radix

Pharmacy Fundamentals | 更新时间：2020-08-11

- Quality Regionalization and Environmental Impact Factors Analysis Based on Main Active Ingredients of Stephaniae Tetrandrae Radix
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 26, Issue 12, Pages: 170-176(2020)
- 作者机构：
  
  1.广西中医药大学瑶医药学院，南宁 530001
  2.广西中医药大学中医药科学实验中心，南宁 530001
  3.中央民族大学药学院，北京 100081
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20201112
  CLC： R284.2;R289;R22;R2-031
- Published Online：19 February 2020，
  
  Published：20 June 2020
- 稿件说明：
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杨帆,吴梦丽,高慧等.基于防己主要活性成分的品质区划及环境影响因素分析[J].中国实验方剂学杂志,2020,26(12):170-176.

YANG Fan,WU Meng-li,GAO Hui,et al.Quality Regionalization and Environmental Impact Factors Analysis Based on Main Active Ingredients of Stephaniae Tetrandrae Radix[J].Chinese Journal of Experimental Traditional Medical Formulae,2020,26(12):170-176.
杨帆,吴梦丽,高慧等.基于防己主要活性成分的品质区划及环境影响因素分析[J].中国实验方剂学杂志,2020,26(12):170-176. DOI： 10.13422/j.cnki.syfjx.20201112.

YANG Fan,WU Meng-li,GAO Hui,et al.Quality Regionalization and Environmental Impact Factors Analysis Based on Main Active Ingredients of Stephaniae Tetrandrae Radix[J].Chinese Journal of Experimental Traditional Medical Formulae,2020,26(12):170-176. DOI： 10.13422/j.cnki.syfjx.20201112.

摘要

目的

基于防己主要活性成分，研究防己品质区划及环境影响因素，为防己优质产区的确定和影响含量的主导环境因子提供参考依据。

方法

基于防己主要活性成分粉防己碱和防己诺林碱及产地环境因子，采用偏最小二乘法回归分析（PLS），主成分分析（PCA）研究防己品质区划及其环境影响因素。

结果

防己诺林碱含量与土壤pH，年均温呈较强正相关，与纬度呈较强负相关；粉防己碱含量与土壤pH呈较强正相关，与经度和年降雨量呈较强负相关；总含量与土壤pH，年均温呈较强正相关，与年降雨量及经度和纬度呈较强负相关。主成分分析结果表明，针对品质形成，50个产区可划分为4个类群，其中广东始兴县、安徽歙县、福建松溪县、广东南雄市、湖南湘乡市防己主成分含量得分较高，为品质形成较佳区域。

结论

土壤pH，年均温，年降雨量，经度和纬度为影响防己药材主要活性成分的主导环境因子。品质较优防己生产区为广东始兴县、安徽歙县、福建松溪县、广东南雄市、湖南湘乡市。

Abstract

Objective

To investigate the quality regionalization and environmental impact factors of Stephaniae Tetrandrae Radix based on main active ingredients，and provide a reference for the determination of high-quality production areas and the dominant environmental factors affecting the content of Stephaniae Tetrandrae Radix.

Method

Partial least squares regression analysis (PLS) and principal component analysis (PCA) were used to study the quality regionalization and environmental impact factors based on the main active ingredients of tetrandrine and fangchinoline

and investigate the environmental factors of the producing areas.

Result

The content of fangchinoline was positively correlated with soil pH and annual average temperature，negatively correlated with latitude. The content of tetrandrine was positively correlated with soil pH，negatively correlated with annual rainfall and longitude. The total content was positively correlated with soil pH and annual average temperature，but negatively correlated with annual rainfall，latitude and longitude. Principal component analysis showed that the 50 production areas could be divided into four groups of quality formation. The groups with the highest scores were Shixing county in Guangdong，Shexian county in Anhui，Songxi county in Fujian，Nanxiong city in Guangdong and Xiangxiang city in Hunan，all of which were best areas for accumulation of the two main active ingredients.

Conclusion

Soil pH，annual average temperature，annual rainfall，latitude and longitude are the main environmental factors affecting the main active ingredients of Stephaniae Tetrandrae Radix. The best areas for accumulation of tetrandrine and fangchinoline are Shixing county in Guangdong，Shexian county in Anhui，Songxi county in Fujian，Nanxiong city in Guangdong and Xiangxiang city in Hunan.

关键词

Keywords

references

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