Objective

2

To investigate the clinical efficacy of Simiaosan combined with arthroscopic radiofrequency ablation in the treatment of acute traumatic knee synovitis and its effects on inflammatory markers and knee joint function.

Method

2

A total of 92 patients with acute traumatic knee synovitis who were treated in our hospital from February 2017 to November 2018 were randomly divided into observation group and control group

with 46 cases in each group. The patients in observation group were treated with Simiaosan combined with arthroscopic radiofrequency ablation

while the patients in control group were treated radiofrequency ablation combined with Gubi tablet

synovitis granule and imrecoxib tablets. The efficacy in the two groups was observed one month after operation. The degree of pain and the swelling of knee joint were evaluated before and one month after operation

and the function of knee joint was evaluated by lysholm knee score system (LKSS) before and one month after operation. And at the same time

the knee joint activity was measured

erythrocyte sedimentation rate (ESR) was analyzed by Wechsler's method

and hypersensitivity C-reactive protein (hs-CRP) was detected by immunoturbidimetry. The adverse reactions and complications of the two groups were observed.

Result

2

Compared with control group after treatment

the total effective rate in observation group was significantly higher than that in control group

with statistically significant differences (

P

<

0.05). The visual analogue scale (VAS) scores of knee pain in both groups after treatment were significantly lower than those before treatment (

P

<

0.05)

while the joint swelling scores were significantly higher (

P

<

0.05). After treatment

the VAS score of knee pain in observation group was significantly lower than that of control group at the same time (

P

<

0.05)

while the joint swelling score was significantly higher (

P

<

0.05). After treatment

the LKSS score and the range of motion of the affected knee joints in both groups were significantly increased compared with those before treatment (

P

<

0.05)

but with more significant improvement in observation group (

P

<

0.05). The levels of ESR in peripheral blood and hs-CRP in serum of the two groups were significantly lower than those before treatment (

P

<

0.05)

especially in observation group (

P

<

0.05). No obvious side effects were observed in observation group during the treatment with Simiaosan. There was no significant difference in the incidence of complications between the two groups.

Conclusion

2

The treatment of Simiaosan combined with radiofrequency ablation under arthroscope has a significant efficacy in the treatment of acute traumatic gonarthromeningitis. The knee joint function of the patients was significantly improved

and the mechanism may be related to the inhibition of inflammatory reaction

in vivo

.