Treatment of Myocardial Injury from Coronavirus Disease-2019 by Chinese Medicine

Li SHEN; Dan-li TANG; Hong-xin CAO

doi:10.13422/j.cnki.syfjx.20201926

您当前的位置：

首页 >

文章列表页 >

Treatment of Myocardial Injury from Coronavirus Disease-2019 by Chinese Medicine

Topic on Epidemic Resistance | 更新时间：2020-09-16

- Treatment of Myocardial Injury from Coronavirus Disease-2019 by Chinese Medicine
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 26, Issue 19, Pages: 80-83(2020)
- 作者机构：
  
  1.中国中医科学院中医基础理论研究所，北京 100700
  2.中国中医科学院医学实验中心，北京 100700
  3.中华中医药学会，北京 100029
- 作者简介：
- 基金信息：
- DOI：10.13422/j.cnki.syfjx.20201926
  CLC： R22;R242;R2-031;R287
- Received：23 May 2020，
  
  Published Online：23 July 2020，
  
  Published：05 October 2020
- 稿件说明：
移动端阅览
申力,唐丹丽,曹洪欣.中医药治疗新型冠状病毒肺炎心肌损伤[J].中国实验方剂学杂志,2020,26(19):80-83.

SHEN Li,TANG Dan-li,CAO Hong-xin.Treatment of Myocardial Injury from Coronavirus Disease-2019 by Chinese Medicine[J].Chinese Journal of Experimental Traditional Medical Formulae,2020,26(19):80-83.
申力,唐丹丽,曹洪欣.中医药治疗新型冠状病毒肺炎心肌损伤[J].中国实验方剂学杂志,2020,26(19):80-83. DOI： 10.13422/j.cnki.syfjx.20201926.

SHEN Li,TANG Dan-li,CAO Hong-xin.Treatment of Myocardial Injury from Coronavirus Disease-2019 by Chinese Medicine[J].Chinese Journal of Experimental Traditional Medical Formulae,2020,26(19):80-83. DOI： 10.13422/j.cnki.syfjx.20201926.

摘要

新型冠状病毒肺炎（COVID-19）心肌损伤是新型冠状病毒感染后出现的一种临床征象，伴随着罹患COVID-19后出现，或见于急性发病期的普通型与重症，或于COVID-19临床痊愈后发病，概由疫毒邪气由口、鼻而入，客于肺卫，肺朝百脉、心主血脉，肺脏受邪，累及于心，气血不畅而发为心肌损伤。通过治疗100余例确诊COVID-19与出院康复患者，发现部分新型冠状病毒感染患者出现心悸、气短、胸痛、胸憋闷、乏力等症状，检查所见心电图心肌缺血损伤、心肌酶升高等，表现温邪上受，首先犯肺、逆传于心的病理变化。新型冠状病毒感染引起心肌损伤，一方面COVID-19患者痊愈出院后，仍有体弱乏力、病情缠绵难愈，另一方面重症患者出现心肌损伤，极易加重病情，甚则危及生命。临床根据发病不同阶段、病情轻重程度及康复期与患者体质采用不同的证治方法。急性重型COVID-19病患心肌损伤，可用生脉饮、急救回阳汤等加减，毒热扰乱心神可酌情使用安宫牛黄丸、至宝丹等；对普通型COVID-19出现心肌损伤，可用竹叶石膏汤与升陷汤加减；对COVID-19临床痊愈后以心肌损伤为主的病理变化用升陷汤、养心汤和柴陷汤等化裁，运用解毒益气养阴、益气升陷、活血化痰等方法治疗COVID-19心肌损伤，能有效改善临床症状，使心肌酶与心电图恢复正常范围，疗效满意，体现中医药治疗COVID-19心肌损伤的整体优势。

Abstract

Myocardial injury from coronavirus disease-2019 (COVID-19) is a clinical sign after the novel coronavirus infection

which can be seen in common type and severe type in acute stage

or after recovery of COVID-19. From the mouth and nose

the epidemic and pathogenic factors enter the lung

involving the heart

so that Qi and blood are blocked and developed into myocardial injury. More than 100 patients with COVID-19 and rehabilitation were treated

and we found that some patients infected with novel coronavirus had palpitation

shortness of breath

chest pain

chest oppression

fatigue and other symptoms. Electrocardiogram(ECG) showed myocardial ischemia injury and increased myocardial enzymes

due to the pathological changes of warm pathogen

first invading the lung and reversely spreading to the heart. Myocardial injury due to infection of novel coronavirus

on the one hand

made the patients weak and conditions lingering and hard to heal after COVID-19 was recovered in discharged patients. On the other hand

myocardial injury in severe cases could easily aggravate the disease and even threaten life. According to the different stages of the disease

the severity of the disease

and the patients' physique in the recovery period

different treatment methods were adopted. For the myocardial injury in patients with acute severe COVID-19

Shengmaiyin and Emergency Huiyangtang can be taken， if the poisonous heat disturbs the mind

we can use Angong Niuhuangwan and Zhibaodan as appropriate. For myocardial injury occurred in common type of COVID-19

Zhuye Shigaotang and Shenxiantang can be used. For the pathological changes mainly including myocardial injury after clinical recovery of COVID-19

we can use Shengxiantang

Yangxintang

Chaixiantang and so on. Methods of detoxification

tonifying Qi and Yin

invigorating Qi and ascending Qi collapse

blood circulation and phlegm resolving were used for treatment of myocardial injury from COVID-19

which can not only effectively improve clinical symptoms

but also restore creatine kinase isoenzyme-MB(CPK-MB) and ECG levels to obtain satisfactory results. All of these could reflect that TCM has a notable advantage in the prevention and treatment of this disease.

关键词

Keywords

references

LIPPI G ， LAVIE C J ， SANCHIS-GOMAR F ， et al . Cardiac troponin I in patients with coronavirus disease 2019 (COVID-19): evidence from a Meta-analysis [J]. Prog Cardiovasc Dis ， 2020 ， doi: 10.1016/j.pcad.2020.03.001 http://dx.doi.org/10.1016/j.pcad.2020.03.001 .

SANTOSO A ， PRANATA R ， WIBOWO A ， et al . Cardiac injury is associated with mortality and critically ill pneumonia in COVID-19:a Meta-analysis [J]. Am J Emerg Med ， 2020 ， doi: 10.1016/j.ajem.2020.04.052 http://dx.doi.org/10.1016/j.ajem.2020.04.052 .

SHI S ， QIN M ， SHEN B ， et al . Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan，China [J]. JAMA Cardiol ， 2020 ， doi: 10.1001/jamacardio.2020.0950 http://dx.doi.org/10.1001/jamacardio.2020.0950 .

蔡秋杰，张华敏，王乐，等 . 论寒疫与新型冠状病毒肺炎(COVID-19)防治 [J]. 中医药信息， 2020 ， 37 ( 2 )： 1 - 5 .

范逸品，王燕平，张华敏，等 . 试析从寒疫论治新型冠状病毒肺炎 [J]. 中医杂志， 2020 ， 61 ( 5 )： 369 - 374

HUANG C ， WANG Y ， LI X ， et al . Clinical features of patients infected with 2019 novel coronavirus in Wuhan，China [J]. Lancet ， 2020 ， 395 ( 10223 )： 497 - 506 .

XU X ， CHEN P ， WANG J ， et al . Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission [J]. Sci Chin Life Sci ， 2020 ， 63 ( 3 )： 457 - 460 .

郭栋，郭万刚，刘鹏云，等 . 新型冠状病毒感染的心脏表现 [J]. 心脏杂志， 2020 ， 32 ( 1 )： 75 - 77 .

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Underlying Mechanisms of Huashi Baidu Prescription Against Myocardial Injury Based on "Transcriptome-Putative Target-Phenotype Gene" Interactions

Mechanism of Ferroptosis in Myocardial Cells and Protective Effect of Traditional Chinese Medicine

Immunomodulatory Mechanism of Kangxian Yixin Prescriptions on Autoimmune Injury Mice Based on Th17/Treg Cell Balance

Clinical Research of Qingkailing Injection in Adjuvant Treatment of Sepsis and Heat Syndrome in Children

Mechanism of Sleep Deprivation and Cognitive Impairment and Research Progress of Traditional Chinese Medicine Intervention

Related Author

LI Weijie

ZHONG Yute

GONG Tian

XIA Cong

WANG Ping

SONG Lijuan

LI Haoran

CAO Ce

Related Institution

NMPA Key Laboratory for Research and Evaluation of Traditional Chinese Medicine

State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs， Institute of Chinese Materia Medica， China Academy of Chinese Medical Sciences

Beijing Key Laboratory of TCM Pharmacology，Xiyuan Hospital，China Academy of Chinese Medical Sciences，National Research Center for Clinical Medicine of Cardiovascular Diseases of TCM

Research Institute of Traditional Chinese Medicine （TCM） of Guangdong Pharmaceutical University

Henan Province Hospital of TCM

AI问答

Postal code：100700
Tel：010-84076882 Email：syfjx_2010@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备11006657号-10 京公网安备11010802024621
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰