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Improvement of Colonic Mucosa Inflammatory Response in Mice with Ulcerative Colitis by Xiezhuo Jiedu Recipe Through miRNA-155-5p/JAK2/STAT3 Pathway
更新时间:2024-04-30
    • Improvement of Colonic Mucosa Inflammatory Response in Mice with Ulcerative Colitis by Xiezhuo Jiedu Recipe Through miRNA-155-5p/JAK2/STAT3 Pathway

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    • The latest research has found that the formula for relieving turbidity and detoxification intervenes in SOCS1 by regulating miR-155-5p expression, inhibiting STAT3 phosphorylation, reducing pro-inflammatory cytokine levels, and alleviating colonic mucosal inflammation in mice with ulcerative colitis.
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 30, Issue 11, Pages: 174-182(2024)
    • DOI:10.13422/j.cnki.syfjx.20231711    

      CLC: R284;R285;R289;R287;R22;R2-031;R33;R24
    • Received:21 September 2023

      Published Online:08 December 2023

      Published:05 June 2024

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  • SUN Chaodi,ZHAO Mengmeng,LANG Xiaomeng,et al.Improvement of Colonic Mucosa Inflammatory Response in Mice with Ulcerative Colitis by Xiezhuo Jiedu Recipe Through miRNA-155-5p/JAK2/STAT3 Pathway[J].Chinese Journal of Experimental Traditional Medical Formulae,2024,30(11):174-182. DOI: 10.13422/j.cnki.syfjx.20231711.

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Related Author

CHUAI Qiang
ZHAI Wenjing
REN Shijie
LANG Xiaomeng
KANG Xin
WEI Wenli
LIU Jingyuan
LIU Jianping

Related Institution

Graduate School, Hebei University of Chinese Medicine
Laboratory of Integrated Chinese and Western Medicine for Gastroenterology Research Hebei
Hebei Key Laboratory of Turbidity Toxin Syndrome
Hebei Provincial Hospital of Traditional Chinese Medicine(TCM)
Handan Hospital of TCM
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