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Combination of Components from Tripterygii Radix et Rhizoma-Chuanxiong Rhizoma Affects RA-FLSs by Regulating NF-κB， Nrf2/HO-1 Signaling Pathways and Bcl-2/Caspase-3 Expression
更新时间：2024-12-24

    • Combination of Components from Tripterygii Radix et Rhizoma-Chuanxiong Rhizoma Affects RA-FLSs by Regulating NF-κB， Nrf2/HO-1 Signaling Pathways and Bcl-2/Caspase-3 Expression

    • “In the field of rheumatoid arthritis treatment, researchers have found that the combination of Tripterygium wilfordii and Ligusticum chuanxiong can effectively inhibit the proliferation and invasion of fibroblast like synovial cells, promote apoptosis, alleviate oxidative stress and inflammation. Its mechanism may be related to the inhibition of NF - κ B signaling, activation of Nrf2/HO-1 pathway, and regulation of Bcl-2/Caspase-3 apoptosis protein expression.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 31, Issue 2, Pages: 17-26(2025)

    • DOI：10.13422/j.cnki.syfjx.20241607    

      CLC： R285;R243;R277

    • Received：31 July 2024，

      Published Online：23 October 2024，

      Published：20 January 2025

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  • GUAN Yongmei,WAN Zhiyan,WANG Shuhui,et al.Combination of Components from Tripterygii Radix et Rhizoma-Chuanxiong Rhizoma Affects RA-FLSs by Regulating NF-κB， Nrf2/HO-1 Signaling Pathways and Bcl-2/Caspase-3 Expression[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(02):17-26. DOI： 10.13422/j.cnki.syfjx.20241607.

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GUAN Yongmei
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