HUANG Xiao-bo, CHEN Wen-qiang, WANG Ning-qun, et al. Intervention of Serum 3-deoxyglucosone by Naokang Ⅱ in Rats with Diabetes Mellitus and Cognitive Impairment[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(10): 119-121.
DOI:
HUANG Xiao-bo, CHEN Wen-qiang, WANG Ning-qun, et al. Intervention of Serum 3-deoxyglucosone by Naokang Ⅱ in Rats with Diabetes Mellitus and Cognitive Impairment[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(10): 119-121. DOI: CNKI:11-3495/R.20110321.1137.014.
Intervention of Serum 3-deoxyglucosone by Naokang Ⅱ in Rats with Diabetes Mellitus and Cognitive Impairment
Objective: To study the influence of Naokang Ⅱ on diabetes mellitus and cognitive impairment in rats. Method :We used Naokang Ⅱ to treat rats with diabetes mellitus and cognitive impairment. We observed the change of rat’s ability of learning and memory function
by the application of water maze
and examined the blood serum 3-deoxyglucosone using gas chromatography-mass spectrometry. Result: Naokang Ⅱcould not reduce rats serum glucose
but it could significantly reduce the swimming time to platform and serum 3-deoxyglucosone. Conclusion: Naokang Ⅱ could improve diabetes mellitus rat’s cognitive impairment
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