ZHANG Guo-song, FENG Chuan-hua, LUO Xiao-jian, et al. Hemolytic Effects of Extraction of Saikosaponins [J]. Chinese journal of experimental traditional medical formulae, 2011, 17(20): 166-169.
DOI:
ZHANG Guo-song, FENG Chuan-hua, LUO Xiao-jian, et al. Hemolytic Effects of Extraction of Saikosaponins [J]. Chinese journal of experimental traditional medical formulae, 2011, 17(20): 166-169. DOI: CNKI:11-3495/R.20110823.1118.012.
Objective: To study hemolytic effect of extraction of saikosaponins and antioxidants on the hemolytic effect of extraction of saikosaponins. Method: The hemolytic effects by different concentrations of saikosaponins and antioxidant effects of saikosaponins hemolytic were observed by naked eye and UV. Result: For saikosaponins with concentrations of 0.01
0.02 g·L-1
its hemolytic curve showed s-shaped
hemolytic equivalent was 0.01 mg
hemolytic index was 1 ∶100 000
antioxidant and saikosaponins group hemolytic rate was lower than the concentration of saikosaponins group. Conclusion: Saikosaponins has hemolytic effect with a certain degree
and hemolytic strength and concentration is dose-dependent
addition of antioxidants can reduce the hemolytic effect of saikosaponins.