WANG Yu-lei, HUANG Shi-jing, CHI De-jun, et al. Study on Stability of Main Iridoid Glucosides from Morindae Officinalis Radix[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 65-68.
DOI:
WANG Yu-lei, HUANG Shi-jing, CHI De-jun, et al. Study on Stability of Main Iridoid Glucosides from Morindae Officinalis Radix[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 65-68. DOI: CNKI:11-3495/R.20110906.1109.007.
Study on Stability of Main Iridoid Glucosides from Morindae Officinalis Radix
Objective: To study stability and transformation of monotropein and deacetylaspcrulosidic acid
which were the main iridoid glucosides from Morindae Officinalis Radix. Method: The content of monotropein and deacetylaspcrulosidic acid from different years of Morindae Officinalis Radix were determined by HPLC to find out the stability in plants. The conversion of monotropein and deacetylaspcrulosidic acid in artificial gastric
water and artificial intestinal juice was studied to seek the stability in different pH solution. Result: The content ratio of monotropein and deacetylaspcrulosidic acid from different years of Morindae Officinalis Radix maintain similar. Monotropein converted to deacetylaspcrulosidic acid in artificial gastric. Conclution: The contents of monotropein and deacetylaspcrulosidic acid is relatively stable in Morindae Officinalis Radix. Monotropein can converted to deacetylaspcrulosidic acid in acidic condition.