MAO Jing-jing, ZHANG Tong, WANG Bing, et al. Research Progress on Pharmacological Activity of 20(S)-protopanaxadiol[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 274-277.
DOI:
MAO Jing-jing, ZHANG Tong, WANG Bing, et al. Research Progress on Pharmacological Activity of 20(S)-protopanaxadiol[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 274-277. DOI: CNKI:11-3495/R.20111017.0941.008.
Research Progress on Pharmacological Activity of 20(S)-protopanaxadiol
Objective :To review and analyze the research papers of 20(S)-protopanaxadiol pharmacological activity. Method :References in CNKI
Wan Fang VIP
Springer
Pubmed
Ovid and other databases were accessed for 20(S)-protopanaxadiol
an active compound of troditional Chinese medicine.Some thirty papers in the past 15 years home and abroad were summarized statistically for its pharmacological activity by popularity. Result :20(S)-protopanaxadiol has anti-cancer
anti-depressant actions. It also shows actions of activating chloride ion channel
inhibiting the depolarization of activated sodium Channel
and inhibiting the growth of human embryonic kidney HEK-293 cells and Helicobacter pylori and many other pharmacological activity. Conclusion : The 20(S)-protopanaxadiol's pharmacological activities are comprehensively summarized
which may give a reference for the medical researchers to carry out the 20(S)-protopanaxadiol pharmacological research in the future. For new drug development
studies on pharmacological mechanisms and toxicity should be carried out in the futnre.