This study investigated the applications of calcium phosphate cement (CPC) as drug deliver system. There is strong evidence that calcium phosphate cement is a nice drug deliver vector. Due to its unique properties

much attention has paied to CPC for drug deliver applications in both areas of research and application. In recent decades

different drugs have been loaded in CPC

including antibiotic(tobramycin

gentamicin and clindamycin)

anti-tumor drugs (adriamycin

mitomycin

vincristine) and cell factors (bone morphogenetic protein and fibrin glue). Particularly

traditional Chinese medicines (astraglycan

Xiangdan injection

Danhong injection

Danshen injection) used in the drug delivery system were summarized to provide the reference for the further improvement of herbal remedies loaded in CPC as a drug delivery system to treat bone disease.