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Mechanisms of Spermatogenic Dysfunction and Sperm Quality Degradation Induced by Propylthiouracil via Endoplasmic Reticulum Stress in Rats and Interventional Effect of Shugan Bushen Yulin Decoction
更新时间：2025-04-02
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    • Mechanisms of Spermatogenic Dysfunction and Sperm Quality Degradation Induced by Propylthiouracil via Endoplasmic Reticulum Stress in Rats and Interventional Effect of Shugan Bushen Yulin Decoction

    • “Shugan Bushen Yulin Tang improves the dysfunction of testicular spermatogenesis and the decrease in sperm quality caused by PTU in rats. It repairs oxidative damage, regulates the endoplasmic reticulum stress PERK/EIF2 α/ATF4 signaling pathway, and alleviates apoptosis of spermatogenic cells.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 31, Issue 9, Pages: 79-89(2025)

    • DOI：10.13422/j.cnki.syfjx.20241639    

      CLC： R242;R289;R278

    • Received：04 July 2024，

      Accepted：2024-09-20，

      Published Online：26 September 2024，

      Published：05 May 2025

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  • MENG Yuhao,JIANG Xiaocui,XIAO Min,et al.Mechanisms of Spermatogenic Dysfunction and Sperm Quality Degradation Induced by Propylthiouracil via Endoplasmic Reticulum Stress in Rats and Interventional Effect of Shugan Bushen Yulin Decoction[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(09):79-89. DOI： 10.13422/j.cnki.syfjx.20241639.

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