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Mechanisms of Spermatogenic Dysfunction and Sperm Quality Degradation Induced by Propylthiouracil via Endoplasmic Reticulum Stress in Rats and Interventional Effect of Shugan Bushen Yulin Decoction
更新时间：2025-04-02

    • Mechanisms of Spermatogenic Dysfunction and Sperm Quality Degradation Induced by Propylthiouracil via Endoplasmic Reticulum Stress in Rats and Interventional Effect of Shugan Bushen Yulin Decoction

    • “Shugan Bushen Yulin Tang improves the dysfunction of testicular spermatogenesis and the decrease in sperm quality caused by PTU in rats. It repairs oxidative damage, regulates the endoplasmic reticulum stress PERK/EIF2 α/ATF4 signaling pathway, and alleviates apoptosis of spermatogenic cells.”
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 31, Issue 9, Pages: 79-89(2025)

    • DOI：10.13422/j.cnki.syfjx.20241639    

      CLC： R242;R289;R278

    • Received：04 July 2024，

      Accepted：20 September 2024，

      Published Online：26 September 2024，

      Published：05 May 2025

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  • MENG Yuhao,JIANG Xiaocui,XIAO Min,et al.Mechanisms of Spermatogenic Dysfunction and Sperm Quality Degradation Induced by Propylthiouracil via Endoplasmic Reticulum Stress in Rats and Interventional Effect of Shugan Bushen Yulin Decoction[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(09):79-89. DOI： 10.13422/j.cnki.syfjx.20241639.

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Related Author

LIU Yiqun
XIAO Min
JIANG Xiaocui
MENG Yuhao
CHEN Siyi
YU Xiaoming
WANG Chaoyang
SHANG Zucheng

Related Institution

College of Traditional Chinese Medicine， Hubei University of Chinese Medicine
Academy of Integrative Medicine，Fujian University of TCM
Fujian University of Traditional Chinese Medicine（TCM）
Guang'anmen Hospital，China Academy of Chinese Medical Sciences
Institute of Chinese Materia Medica， China Academy of Chinese Medical Sciences
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