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1.长沙市第一医院,长沙 410005
2.湖南中医药大学 附属第二医院,长沙 410005
张扬,硕士,主治医师,从事中西医结合脑病防治研究,E-mail:317725106@qq.com
湛韬,博士,副主任医师,从事中西医结合脑病防治研究,E-mail:874147480@qq.com
纸质出版日期:2022-12-05,
网络出版日期:2022-08-12,
收稿日期:2022-04-08,
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张扬,毛以林,陈美平等.长沙地区收治新冠病毒Delta和Omicron变异株感染者中医辨证分析[J].中国实验方剂学杂志,2022,28(23):117-121.
ZHANG Yang,MAO Yilin,CHEN Meiping,et al.Traditional Chinese Medicine Syndrome Differentiation of Delta and Omicron Variants of SARS-CoV-2 Carriers in Changsha, Hunan[J].Chinese Journal of Experimental Traditional Medical Formulae,2022,28(23):117-121.
张扬,毛以林,陈美平等.长沙地区收治新冠病毒Delta和Omicron变异株感染者中医辨证分析[J].中国实验方剂学杂志,2022,28(23):117-121. DOI: 10.13422/j.cnki.syfjx.20222394.
ZHANG Yang,MAO Yilin,CHEN Meiping,et al.Traditional Chinese Medicine Syndrome Differentiation of Delta and Omicron Variants of SARS-CoV-2 Carriers in Changsha, Hunan[J].Chinese Journal of Experimental Traditional Medical Formulae,2022,28(23):117-121. DOI: 10.13422/j.cnki.syfjx.20222394.
目的
2
总结比较新冠病毒Delta和Omicron变异株感染者的主要中医病机,为新冠病毒感染的证型演变和辨证思路提供参考。
方法
2
收集2021年9月23日至2022年3月27日长沙地区收治的境外输入性及本土新冠病毒Delta和Omicron变异株阳性病例的中医诊治资料,其中Delta变异株感染者18例,Omicron变异株感染者36例,分析对比患者的四诊信息和中医病机。
结果
2
Delta株感染确诊患者以咳嗽、发热、胸闷/呼吸困难、身体酸痛、恶心、口干咽干、咽痛、舌苔厚腻、滑数脉多见,病机以上焦湿热、少阳郁热挟湿为主,其中胸闷/呼吸困难、腻苔、滑脉及判断为上焦湿热证的比例较Omicron株感染者更高,差异有统计学意义(
P
<
0.05)。Omicron变异株感染确诊患者以咽痒、咽痛、鼻塞、流涕、发热、轻度畏寒、口干、头晕症状以及淡红舌薄白苔、数脉或弦脉为主要表现,中医病机以风燥犯卫和少阳郁热为主,其中白苔舌象和风燥犯卫证的出现比例较Delta变异株感染者高,差异有统计学意义(
P
<
0.05)。
结论
2
长沙地区收治的新冠病毒Delta和Omicron变异株感染者的中医病机分布有显著区别,Delta变异株感染倾向于表现为“湿热”特征,而Omicron变异株感染倾向于表现为“风燥”特征,这一差别可为新冠病毒感染的病机演化规律提供参考。
Objective
2
To summarize and compare the main traditional Chinese medicine (TCM) syndromes of Delta and Omicron variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) carriers to provide references for the syndrome evolution and syndrome differentiation of SARS-CoV-2 infection.
Method
2
The TCM medical records of imported and local cases of infection with Delta and Omicron variants of SARS-CoV-2 in Changsha since September 23, 2021 to March 27, 2022 were collected, including 18 Delta variant cases and 36 Omicron variant cases. Their TCM diagnosis information and TCM pathogenesis were analyzed and compared.
Result
2
The common manifestations in Delta variant cases were cough, fever, chest distress/shortness of breath, sore muscles, nausea, dry mouth, dry or sore throat, thick and greasy tongue coating, and rapid and slippery pulse. The predominant pathogenesis was dampness-heat in the upper-energizer and heat stagnation in the lesser Yang combined with dampness. The occurrence of chest distress/shortness of breath, greasy tongue coating, slippery pulse, and the proportion of dampness-heat in the upper-energizer syndrome were higher in Delta variant cases than in Omicron variant cases (
P
<
0.05). The common manifestations in Omicron variant cases were itchy and sore throat, nasal congestion, running nose, fever, mild aversion to cold, dry mouth, dizziness, slightly reddish tongue with thin white coating, and rapid or wiry pulse. The predominant pathogenesis was wind-dryness invading defensive exterior, and heat stagnation in the lesser Yang. The occurrence of white-coated tongue and the proportion of wind-dryness invading defensive exterior syndrome were higher in Omicron variant cases than in Delta variant cases (
P
<
0.05).
Conclusion
2
There are certain differences in TCM syndromes and the corresponding pathogenesis between Delta variant and Omicron variant cases in Changsha, Hunan. The Delta variant of SARS-COV-2 tends to induce dampness-heat syndrome, whereas Omicron variant infection tends to elicit wind-dampness syndrome, which is expected to provide a reference for the pathogenesis evolution of SARS-COV-2 infection.
新型冠状病毒Omicron变异株Delta变异株中医病机证候
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Omicron variantDelta varianttraditional Chinese medicine pathogenesissyndrome
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