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Mechanism of Polyphyllin Ⅱ in Induction of Ferroptosis in Hepatocellular Carcinoma HepG2 Cells
Mechanism of Polyphyllin Ⅱ in Induction of Ferroptosis in Hepatocellular Carcinoma HepG2 Cells
- “Zhonglou Saponin II (PP II) induces ferroptosis in HepG2 liver cancer cells by regulating the p53/SLC7A11/GPX4 signaling pathway axis, promoting ACSL4 expression and cell uptake of Fe3+, and disrupting the antioxidant system.”
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 30, Issue 17, Pages: 105-112(2024)
DOI： 10.13422/j.cnki.syfjx.20240629
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Related Author
RUAN Yidan
ZHANG Huizhong
HUANG Huating
ZHANG Pingzhi
YAO Aina
ZHANG Yongqiang
XU Xiaohan
LI Shiman
Related Institution
School of Chinese Material Medica， Beijing University of Chinese Medicine
The First School of Clinical Medicine， Shaanxi University of Chinese Medicine
Affiliated Hospital of Shaanxi University of Chinese Medicine
Gansu University of Traditional Chinese Medicine
Shandong University of Traditional Chinese Medicine（TCM）
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