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Multi-targeting Action Mechanism of Wenyang Xiaoyin Prescription on Doxorubicin-induced Mouse with Chronic Heart Failure Based on NF-κB/AVP-AQP2 Complex Pathway Mediated by Liver X Receptor
Updated：2026-06-18
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    • Multi-targeting Action Mechanism of Wenyang Xiaoyin Prescription on Doxorubicin-induced Mouse with Chronic Heart Failure Based on NF-κB/AVP-AQP2 Complex Pathway Mediated by Liver X Receptor

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    • “The Wenyang Xiaoyin formula has a significant therapeutic effect on a mouse model of chronic heart failure. Based on the liver X receptor mediated arginine vasopressin/antidiuretic hormone V2 receptor/aquaporin type 2 signaling pathway and nuclear transcription factor - κ B pathway in the heart brain kidney tissue, the multi-target mechanism of this treatment is revealed, providing a new approach for the prevention and treatment of heart failure in traditional Chinese medicine.”
    • LI Baixue , ZHAO Junfeng , ZHANG Song , LIU Lei , PENG Yangzhi , ZHOU Hang
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 14, Pages: 286-297(2026)

    • DOI： 10.13422/j.cnki.syfjx.20250313     

      CLC：

    • Revised：2025-02-08 ，

      Accepted：08 February 2025 ，

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