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Mechanism of Action of Huangqi Guizhi Wuwutang Against Cerebral Ischemia-reperfusion Injury Based on Bioinformatics and Experimental Validation
更新时间:2025-10-16
    • Mechanism of Action of Huangqi Guizhi Wuwutang Against Cerebral Ischemia-reperfusion Injury Based on Bioinformatics and Experimental Validation

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    • According to the latest research report, Huangqi Guizhi Wuwu Tang reduces cell apoptosis, inflammatory response, and oxidative stress in rat brain tissue after CIRI by regulating the phosphorylation levels of Akt1 and STAT3, exerting neuroprotective effects and providing theoretical support for clinical treatment of CIRI.
    • Chinese Journal of Experimental Traditional Medical Formulae   Vol. 31, Issue 22, Pages: 10-20(2025)
    • DOI:10.13422/j.cnki.syfjx.20250718    

      CLC: R743.31;R285;R289
    • Received:11 May 2025

      Revised:2025-06-16

      Accepted:23 June 2025

      Published Online:02 July 2025

      Published:20 November 2025

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  • HU Jie,TANG Gaojun,RAO Ouyang,et al.Mechanism of Action of Huangqi Guizhi Wuwutang Against Cerebral Ischemia-reperfusion Injury Based on Bioinformatics and Experimental Validation[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(22):10-20. DOI: 10.13422/j.cnki.syfjx.20250718.

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Related Author

HU Jie
LIU Ying
ZHANG Weichao
LI Yayun
GAO Tianci
HOU Mengxing
XU Wenzhong
CHEN Fenqiao

Related Institution

Graduate School, Hebei University of Chinese Medicine
The First Affiliated Hospital,Hebei University of Chinese Medicine
The First Affiliated Hospital of Henan University of Chinese Medicine
The First Clinical Medical School,Henan University of Chinese Medicine
Key Laboratory of Chemistry and Engineering of Forest Products, National Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products/Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, School of Chemistry and Chemical Engineering, Guangxi Minzu University
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