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Mechanism of Shenmai Injection to Improve Cisplatin Resistance in NSCLC Based on Endoplasmic Reticulum Stress Through PERK/ATF4/CHOP Signaling Pathway
Updated：2026-01-23
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    • Mechanism of Shenmai Injection to Improve Cisplatin Resistance in NSCLC Based on Endoplasmic Reticulum Stress Through PERK/ATF4/CHOP Signaling Pathway

    • “The latest research has found that the combination of Shenmai injection and cisplatin has a synergistic anti-tumor effect on non-small cell lung cancer, which may be related to activating the endoplasmic reticulum stress PERK/eIF2 α/ATF4/CHOP signaling pathway and inducing tumor cell apoptosis.”
    • GUO Shengnan , CAO Hao , WANG Dan , LIU Wenjun , WANG Jianguang , LYU Jialu , WANG Chun
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 4, Pages: 70-78(2026)

    • DOI： 10.13422/j.cnki.syfjx.20250825     

      CLC：

    • Revised：2025-02-17 ，

      Accepted：21 February 2025 ，

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Related Author

DONG Hanyu
WANG Chun
LIU Chunying
LIU Wenjun
YU Dan
MU Qirui
LI He
LIU Yuetong

Related Institution

Key Laboratory of Ministry of Education for Traditional Chinese Medicine（TCM） Viscera-State Theory and Applications， Liaoning University of TCM
First Clinical College， Liaoning University of TCM
School of Basin Medical Sciences，Liaoning University of TCM
Teaching and Experimental Center，Liaoning University of TCM
College of Integrated Chinese and Western Medicine， Liaoning University of Traditional Chinese Medicine