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Mechanism of Shenmai Injection to Improve Cisplatin Resistance in NSCLC Based on Endoplasmic Reticulum Stress Through PERK/ATF4/CHOP Signaling Pathway
Updated：2026-01-23
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    • Mechanism of Shenmai Injection to Improve Cisplatin Resistance in NSCLC Based on Endoplasmic Reticulum Stress Through PERK/ATF4/CHOP Signaling Pathway

    • “The latest research has found that the combination of Shenmai injection and cisplatin has a synergistic anti-tumor effect on non-small cell lung cancer, which may be related to activating the endoplasmic reticulum stress PERK/eIF2 α/ATF4/CHOP signaling pathway and inducing tumor cell apoptosis.”
    • GUO Shengnan , CAO Hao , WANG Dan , LIU Wenjun , WANG Jianguang , LYU Jialu , WANG Chun
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 4, Pages: 70-78(2026)

    • DOI： 10.13422/j.cnki.syfjx.20250825     

      CLC：

    • Revised：2025-02-17 ，

      Accepted：21 February 2025 ，

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