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Mechanisms of Improving Hippocampal Synaptic Plasticity Through GLP-1/GLP-1r Pathway to Alleviate Anxiety and Depression-like Behaviors in Chronic Restraint Stress Rats by Xiaoyaosan
Updated：2025-12-24
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    • Mechanisms of Improving Hippocampal Synaptic Plasticity Through GLP-1/GLP-1r Pathway to Alleviate Anxiety and Depression-like Behaviors in Chronic Restraint Stress Rats by Xiaoyaosan

    • “The latest research has found that Xiaoyao San can enhance synaptic plasticity and improve anxiety and depression like behavior in chronic restraint stress rats by activating GLP-1/GLP-1r in the hippocampal CA1 region and its mediated PKA/CREB/BDNF signaling pathway.”
    • WANG Hao , YAN Yanan , WANG Jiepeng , FANG Chaoyi , FANG Fang
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 2, Pages: 34-42(2026)

    • DOI： 10.13422/j.cnki.syfjx.20250837     

      CLC：

    • Revised：2025-04-12 ，

      Accepted：16 April 2025 ，

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