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1.上海中医药大学 附属岳阳中西医结合医院,上海 200437
2.上海市中医药研究院 皮肤病研究所,上海 200437
3.现代中药创制全国重点实验室,天津 300410
4.中华中医药学会,北京 100029
Received:06 November 2024,
Accepted:07 January 2025,
Published Online:08 January 2025,
Published:05 March 2025
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刘柳,孙晓颖,莫美等.中医药临床优势病种探讨——银屑病[J].中国实验方剂学杂志,2025,31(05):260-268.
LIU Liu,SUN Xiaoying,MO Mei,et al.Clinical Diseases Responding Specially to TCM Treatment: Psoriasis[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(05):260-268.
刘柳,孙晓颖,莫美等.中医药临床优势病种探讨——银屑病[J].中国实验方剂学杂志,2025,31(05):260-268. DOI: 10.13422/j.cnki.syfjx.20250897.
LIU Liu,SUN Xiaoying,MO Mei,et al.Clinical Diseases Responding Specially to TCM Treatment: Psoriasis[J].Chinese Journal of Experimental Traditional Medical Formulae,2025,31(05):260-268. DOI: 10.13422/j.cnki.syfjx.20250897.
银屑病是皮肤科常见的慢性炎症性系统性疾病,其高患病率、复发率及诸多共病为患者带来极大的身心负担。随着现代医学不断革新,银屑病的诊治除经典治疗外,生物制剂的出现提高了临床疗效,使攻克银屑病成为可能。但在临床应用中,不良反应、耐药性、复发率及免疫漂移等现象不容忽视。中医药治疗银屑病经历了数千年实践,疗效好安全性高复发率较低,但缺乏规范的管理体系。因此由中华中医药学会主办,中华中医药学会青年委员会承办的“第二十五期临床优势病种系列(银屑病)青年沙龙”邀请中医、西医和交叉学科的共29位专家学者就“中西医诊疗银屑病的优势、难点、临床转化”等方面展开了积极的讨论。与会专家讨论认为中医药治疗银屑病的优势存在于以下几方面,其一是在以中医药为主导的方案中,中医学对银屑病的认识遵循辨病与辨证相结合的理念,分清基本矛盾和当下的主要矛盾,能够清晰地掌握银屑病发展的动态过程。接着利用辨证论治体系对当下的主要矛盾进行中医药干预,以内治与外治相结合的方式,为患者制定最佳的中医药方案。秉承“有诸内者,必形诸外”的观点,中医学通过辨明证型,可早期防治银屑病共病。其二是在以中西医结合治疗的方案中,中西医结合治疗不仅可协同增效,还能减轻免疫抑制剂、生物制剂等不良反应,降低复发率。此次会议为银屑病的中医及中西医结合诊疗方案及优势提供参考,开拓临床与基础研究的新思路,指导未来研究方向。
Psoriasis is a common chronic inflammatory systemic disease in dermatology. Its high prevalence, recurrence rate, and numerous comorbidities impose a significant physical and mental burden on patients. With the continuous advancement of modern medicine, the emergence of biological agents has improved clinical efficacy, making it possible to overcome psoriasis, in addition to classical treatments. However, in clinical practice, adverse reactions, drug resistance, recurren
ce rates, and immune drift cannot be ignored. Traditional Chinese medicine (TCM) has a history of thousands of years in treating psoriasis, demonstrating good efficacy, high safety, and a low recurrence rate, but a standardized management system is lacking. Therefore, the 25
th
Clinical Diseases Responding Specially to TCM Treatment Series (Psoriasis) Youth Salon, hosted by the Chinese Association of Chinese Medicine and organized by the Youth Committee of the Chinese Association of Chinese Medicine, invited 29 experts and scholars from TCM, Western medicine, and interdisciplinary fields to actively discuss the "Advantages, Challenges, and Clinical Transformation of TCM and Western Medicine in the Diagnosis and Treatment of Psoriasis". The experts at the meeting concluded that the advantages of TCM in the treatment of psoriasis are as follows. Firstly, in the TCM-led treatment plan, TCM's understanding of psoriasis follows the principle of combining the differentiation of disease and syndrome. This approach distinguishes the basic contradiction from the current main contradiction and enables a clear grasp of the dynamic process of psoriasis development. Based on the system of syndrome differentiation and treatment, TCM intervention is applied to address the current main contradiction, and the optimal TCM treatment plan is formulated by combining internal and external treatments. Adhering to the principle of "what is visible outside must be addressed inside", TCM can prevent and treat psoriasis comorbidities early by differentiating syndrome types. Secondly, in the integrated TCM and Western medicine treatment plan, the combination of both methods not only enhances efficacy but also reduces the adverse reactions of immunosuppressants and biological agents, lowering the recurrence rate. This conference provides a reference for the diagnosis and treatment of psoriasis using TCM and integrated TCM and Western medicine, opening up new ideas for clinical and basic research and guiding future research directio
ns.
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