“The pathogenesis of ulcerative colitis is complex, and mitochondrial autophagy can clear damaged mitochondria and reduce inflammatory damage. "The function of spleen in traditional Chinese medicine is similar to the role of mitochondria in energy conversion and substance metabolism, and the pathological state of 'spleen dysfunction' may be related to mitochondrial dysfunction. The pathogenic characteristics of 'endogenous turbid pathogens' are also similar to the inflammatory cascade reaction induced by abnormal release of mtDAMPs." The research team explored the correlation between the theory of' spleen lost essence and endogenous turbid pathogens' and mitochondrial autophagy, opening up new directions for traditional Chinese medicine to prevent and treat ulcerative colitis.”