“Geniposide is the main active ingredient of traditional Chinese medicine Gardenia jasminoides, with various biological activities such as liver protection, anti-inflammatory and analgesic effects, and neuroprotection. In recent years, studies have found that gardenoside also shows good potential in the prevention and treatment of atherosclerosis, osteoporosis and other diseases. However, due to its strong water solubility and rapid metabolism in the body, its oral bioavailability is low, which limits its efficacy and clinical application. To solve this problem, researchers have developed creams, cubic liquid crystals, hydrogels, liposomes and other preparations. This article reviews the pharmacological research and formulation development progress of geniposide in the past 10 years at home and abroad, providing a theoretical basis for its further research and development.”